ID Q1RN33_HUMAN Unreviewed; 317 AA. AC Q1RN33; DT 16-MAY-2006, integrated into UniProtKB/TrEMBL. DT 16-MAY-2006, sequence version 1. DT 23-MAY-2018, entry version 65. DE SubName: Full=Melanoma antigen A 4 {ECO:0000313|EMBL:AAY27261.1}; DE SubName: Full=cDNA, FLJ94494, Homo sapiens melanoma antigen, family A, 4 (MAGEA4), mRNA {ECO:0000313|EMBL:BAG36590.1}; GN Name=MAGEA4 {ECO:0000313|EMBL:AAY27261.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:AAY27261.1}; RN [1] {ECO:0000313|EMBL:AAY27261.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Lung squamous cell carcinoma {ECO:0000313|EMBL:AAY27261.1}; RX PubMed=16651421; DOI=10.1158/0008-5472.CAN-05-3327; RA Peikert T., Specks U., Farver C., Erzurum S.C., Comhair S.A.; RT "Melanoma antigen A4 is expressed in non-small cell lung cancers and RT promotes apoptosis."; RL Cancer Res. 66:4693-4700(2006). RN [2] {ECO:0000313|EMBL:BAG36590.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Testis {ECO:0000313|EMBL:BAG36590.1}; RA Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., RA Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., RA Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., RA Isogai T.; RT "NEDO functional analysis of protein and research application RT project."; RL Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases. CC -!- INTERACTION: CC Q4VCS5-2:AMOT; NbExp=3; IntAct=EBI-10194128, EBI-3891843; CC Q9Y2J4-4:AMOTL2; NbExp=3; IntAct=EBI-10194128, EBI-10187270; CC Q9BXY8:BEX2; NbExp=3; IntAct=EBI-10194128, EBI-745073; CC Q12789:GTF3C1; NbExp=3; IntAct=EBI-10194128, EBI-357956; CC Q8WW24:TEKT4; NbExp=3; IntAct=EBI-10194128, EBI-750487; CC Q53EQ6-2:TIGD5; NbExp=3; IntAct=EBI-10194128, EBI-10242213; CC P04183:TK1; NbExp=3; IntAct=EBI-10194128, EBI-712550; CC Q86WT6:TRIM69; NbExp=3; IntAct=EBI-10194128, EBI-749955; CC Q9BZV1:UBXN6; NbExp=3; IntAct=EBI-10194128, EBI-1993899; CC P14927:UQCRB; NbExp=3; IntAct=EBI-10194128, EBI-743128; CC Q969T9:WBP2; NbExp=3; IntAct=EBI-10194128, EBI-727055; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY954624; AAY27261.1; -; mRNA. DR EMBL; AK313862; BAG36590.1; -; mRNA. DR UniGene; Hs.37107; -. DR IntAct; Q1RN33; 11. DR PRIDE; Q1RN33; -. DR eggNOG; KOG4562; Eukaryota. DR eggNOG; ENOG4111S70; LUCA. DR HOVERGEN; HBG006315; -. DR ChiTaRS; MAGEA4; human. DR InterPro; IPR037445; MAGE. DR InterPro; IPR021072; MAGE_N. DR InterPro; IPR030098; MAGEA4/MAGEA5. DR InterPro; IPR002190; MHD_dom. DR PANTHER; PTHR11736; PTHR11736; 1. DR PANTHER; PTHR11736:SF48; PTHR11736:SF48; 1. DR Pfam; PF01454; MAGE; 1. DR Pfam; PF12440; MAGE_N; 1. DR SMART; SM01373; MAGE; 1. DR SMART; SM01392; MAGE_N; 1. DR PROSITE; PS50838; MAGE; 1. PE 1: Evidence at protein level; FT DOMAIN 110 309 MAGE. {ECO:0000259|PROSITE:PS50838}. SQ SEQUENCE 317 AA; 34929 MW; 3CFAC0E2B696257C CRC64; MSSEQKSQHC KPEEGVEAQE EALGLVGAQA PTTEEQEAAV SSSSPLVPGT LEEVPAAESA GPPQSPQGAS ALPTTISFTC WRQPNEGSSS QEEEGPSTSP DAESLFREAL SNKVDELAHF LLRKYRAKEL VTKAEMLERV IKNYKRCFPV IFGKASESLK MIFGIDVKEV DPTSNTYTLV TCLGLSYDGL LGNNQIFPKT GLLIIVLGTI AMEGDSASEE EIWEELGVMG VYDGREHTVY GEPRKLLTQD WVQENYLEYR QVPGSNPARY EFLWGPRALA ETSYVKVLEH VVRVNARVRI AYPSLREAAL LEEEEGV //