ID Q1MGE1_RHIL3 Unreviewed; 270 AA. AC Q1MGE1; DT 30-MAY-2006, integrated into UniProtKB/TrEMBL. DT 30-MAY-2006, sequence version 1. DT 13-NOV-2007, entry version 12. DE Putative indole-3-glycerol phosphate synthase (EC 4.1.1.48). GN Name=trpC; OrderedLocusNames=RL2494; OS Rhizobium leguminosarum bv. viciae (strain 3841). OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium. OX NCBI_TaxID=216596; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16640791; DOI=10.1186/gb-2006-7-4-r34; RA Young J.P.W., Crossman L.C., Johnston A.W.B., Thomson N.R., RA Ghazoui Z.F., Hull K.H., Wexler M., Curson A.R.J., Todd J.D., RA Poole P.S., Mauchline T.H., East A.K., Quail M.A., Churcher C., RA Arrowsmith C., Cherevach I., Chillingworth T., Clarke K., Cronin A., RA Davis P., Fraser A., Hance Z., Hauser H., Jagels K., Moule S., RA Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M., RA Whitehead S., Parkhill J.; RT "The genome of Rhizobium leguminosarum has recognizable core and RT accessory components."; RL Genome Biol. 7:RESEARCH34.1-RESEARCH34.20(2006). CC -!- CATALYTIC ACTIVITY: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5- CC phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO(2) + H(2)O. CC -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L- CC tryptophan from chorismate: step 4/5. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AM236080; CAK07982.1; -; Genomic_DNA. DR RefSeq; YP_768078.1; -. DR GeneID; 4401273; -. DR GenomeReviews; AM236080_GR; RL2494. DR GO; GO:0004425; F:indole-3-glycerol-phosphate synthase activity; IEA:InterPro. DR GO; GO:0006568; P:tryptophan metabolic process; IEA:InterPro. DR InterPro; IPR013785; Aldolase_TIM. DR InterPro; IPR013798; Indole-3-GPS. DR InterPro; IPR001468; Indole-3-GPS_central. DR Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1. DR Pfam; PF00218; IGPS; 1. DR ProDom; PD001511; IGPS; 1. PE 4: Predicted; KW Amino-acid biosynthesis; Aromatic amino acid biosynthesis; KW Complete proteome; Lyase; Tryptophan biosynthesis. SQ SEQUENCE 270 AA; 29086 MW; AB458A6985C28209 CRC64; MTDILKKIEL YKREEIAAAK ATVSLADLKA MQAGQSAPRG FHKALIAKRD AGRFGLIAEI KKASPSKGLI RPDFDPPSLA SAYEAGGAAC LSVLTDTPSF QGAPEFLTAA RSACTLPALR KDFMFETYQV HEARAWGADC ILLIMASLSD DEAERLQDEA FALGMDVLVE VHDAEEMERA LKLSSPLIGI NNRNLRTFEV SLTVSEALAP MVSADRLLVG ESGIFTHADC KRLQAVDINT FLVGESLMRK EDVAAATRAL LFGEAAIAAE //