ID Q1INB9_KORVE Unreviewed; 260 AA. AC Q1INB9; DT 13-JUN-2006, integrated into UniProtKB/TrEMBL. DT 13-JUN-2006, sequence version 1. DT 27-MAR-2024, entry version 77. DE SubName: Full=Beta-lactamase-like protein {ECO:0000313|EMBL:ABF41631.1}; GN OrderedLocusNames=Acid345_2630 {ECO:0000313|EMBL:ABF41631.1}; OS Koribacter versatilis (strain Ellin345). OC Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae; OC Koribacter. OX NCBI_TaxID=204669 {ECO:0000313|EMBL:ABF41631.1, ECO:0000313|Proteomes:UP000002432}; RN [1] {ECO:0000313|EMBL:ABF41631.1, ECO:0000313|Proteomes:UP000002432} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Ellin345 {ECO:0000313|EMBL:ABF41631.1, RC ECO:0000313|Proteomes:UP000002432}; RX PubMed=19201974; DOI=10.1128/AEM.02294-08; RA Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., RA Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., RA Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., RA Davidsen T.M., DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., RA Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., RA Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., RA Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., RA Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R.; RT "Three genomes from the phylum Acidobacteria provide insight into the RT lifestyles of these microorganisms in soils."; RL Appl. Environ. Microbiol. 75:2046-2056(2009). RN [2] {ECO:0007829|PDB:6B9V} RP X-RAY CRYSTALLOGRAPHY (1.88 ANGSTROMS) IN COMPLEX WITH MN(2+) AND ZN(2+). RX PubMed=29229761; DOI=10.1042/BCJ20170817; RA Beaudoin G.A.W., Li Q., Bruner S.D., Hanson A.D.; RT "An unusual diphosphatase from the PhnP family cleaves reactive FAD RT photoproducts."; RL Biochem. J. 475:261-272(2018). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000360; ABF41631.1; -; Genomic_DNA. DR RefSeq; WP_011523432.1; NC_008009.1. DR PDB; 6B9V; X-ray; 1.88 A; A/B=1-260. DR PDBsum; 6B9V; -. DR AlphaFoldDB; Q1INB9; -. DR SMR; Q1INB9; -. DR STRING; 204669.Acid345_2630; -. DR EnsemblBacteria; ABF41631; ABF41631; Acid345_2630. DR KEGG; aba:Acid345_2630; -. DR eggNOG; COG1235; Bacteria. DR HOGENOM; CLU_044538_2_1_0; -. DR OrthoDB; 9800940at2; -. DR Proteomes; UP000002432; Chromosome. DR CDD; cd16279; metallo-hydrolase-like_MBL-fold; 1. DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1. DR InterPro; IPR001279; Metallo-B-lactamas. DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro. DR PANTHER; PTHR42663:SF6; HYDROLASE C777.06C-RELATED; 1. DR PANTHER; PTHR42663; HYDROLASE C777.06C-RELATED-RELATED; 1. DR Pfam; PF12706; Lactamase_B_2; 1. DR SMART; SM00849; Lactamase_B; 1. DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1. PE 1: Evidence at protein level; KW 3D-structure {ECO:0007829|PDB:6B9V}; Metal-binding {ECO:0007829|PDB:6B9V}; KW Reference proteome {ECO:0000313|Proteomes:UP000002432}; KW Zinc {ECO:0007829|PDB:6B9V}. FT DOMAIN 36..229 FT /note="Metallo-beta-lactamase" FT /evidence="ECO:0000259|SMART:SM00849" FT BINDING 21 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /evidence="ECO:0007829|PDB:6B9V" FT BINDING 23 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /evidence="ECO:0007829|PDB:6B9V" FT BINDING 26 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /evidence="ECO:0007829|PDB:6B9V" FT BINDING 76 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="1" FT /evidence="ECO:0007829|PDB:6B9V" FT BINDING 78 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="1" FT /evidence="ECO:0007829|PDB:6B9V" FT BINDING 80 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="2" FT /evidence="ECO:0007829|PDB:6B9V" FT BINDING 81 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="2" FT /evidence="ECO:0007829|PDB:6B9V" FT BINDING 158 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="1" FT /evidence="ECO:0007829|PDB:6B9V" FT BINDING 176 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="1" FT /evidence="ECO:0007829|PDB:6B9V" FT BINDING 176 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="2" FT /evidence="ECO:0007829|PDB:6B9V" FT BINDING 229 FT /ligand="Mn(2+)" FT /ligand_id="ChEBI:CHEBI:29035" FT /ligand_label="2" FT /evidence="ECO:0007829|PDB:6B9V" FT BINDING 232 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /evidence="ECO:0007829|PDB:6B9V" SQ SEQUENCE 260 AA; 29153 MW; 42E422A445CC224A CRC64; MRATLTVLGS GTSMGVPTIG CDCAVCSSSD PHDRRLRPSV MVQYDGKLVL IDTTPDFREQ ALREGIKKID AIVYTHGHAD HILGLDDVRP LSFPRITGGA RVPLYANEKT ERVLKHVFKY IFDDDYKFGS IAQVEMHRVH HEAIELFGAK FIPVPVIHGE TEIYGYRFGS AAYLTDFSSI PDASMEMLRG LDILFLDALR HKPHPTHSTL DNSVSIAEKL KAKHTYFTHI SHDLPHEETN RQLPAGIQLA HDGLKLEFEL //