ID Q1HL22_MOUSE Unreviewed; 1219 AA. AC Q1HL22; DT 13-JUN-2006, integrated into UniProtKB/TrEMBL. DT 13-JUN-2006, sequence version 1. DT 16-APR-2014, entry version 63. DE SubName: Full=SorCS3; GN Name=Sorcs3; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=BTBR T+ tf/J; RX PubMed=16682971; DOI=10.1038/ng1796; RA Clee S.M., Yandell B.S., Schueler K.M., Rabaglia M.E., Richards O.C., RA Raines S.M., Kabara E.A., Klass D.M., Mui E.T.-K., Stapleton D.S., RA Gray-Keller M.P., Young M.B., Stoehr J.P., Lan H., Boronenkov I., RA Raess P.W., Flowers M.T., Attie A.D.; RT "Positional cloning of Sorcs1, a type 2 diabetes quantitative trait RT locus."; RL Nat. Genet. 38:688-693(2006). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DQ479928; ABF48507.1; -; Genomic_DNA. DR RefSeq; NP_079972.1; NM_025696.3. DR UniGene; Mm.70980; -. DR ProteinModelPortal; Q1HL22; -. DR SMR; Q1HL22; 294-333, 567-664, 804-910. DR PRIDE; Q1HL22; -. DR DNASU; 66673; -. DR GeneID; 66673; -. DR KEGG; mmu:66673; -. DR CTD; 22986; -. DR MGI; MGI:1913923; Sorcs3. DR HOVERGEN; HBG059252; -. DR InParanoid; Q1HL22; -. DR OMA; LDQKLYS; -. DR PhylomeDB; Q1HL22; -. DR NextBio; 322337; -. DR ArrayExpress; Q1HL22; -. DR Bgee; Q1HL22; -. DR Genevestigator; Q1HL22; -. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR Gene3D; 2.60.40.670; -; 1. DR InterPro; IPR000601; PKD_dom. DR InterPro; IPR006581; VPS10. DR Pfam; PF00801; PKD; 1. DR SMART; SM00602; VPS10; 1. DR SUPFAM; SSF49299; SSF49299; 2. DR PROSITE; PS50093; PKD; 1. PE 2: Evidence at transcript level; KW Membrane; Repeat; Transmembrane; Transmembrane helix. SQ SEQUENCE 1219 AA; 135985 MW; ABB3278A2EFEC7C4 CRC64; MEAAGTERPA GWPGAPLART GLLLLSTWVL AGAEITWGAT GGPGRLVSPA SRPPVLPPLL PRAAENRWPE ELASARRAAA PRRRSRLEPL SQASRGEIRT EAAGMSPEGA RWVPGIPSPS QAGSARRTRR AQPPSPLERG DSWATALADG AKGSRPHTKG SREEVRATRT GGASTEELRL PSTSFALTGD SAHNQAMVHW SGHNSSVILI LTKLYDFNLG SVTESSLWRS VDYGATYEKL NDKVGLKTVL SYLYVNPTNK RKIMLLSDPE MESSVLISSD EGATYQKYRL TFYIQSLLFH PKQEDWVLAY SLDQKLYSSM DFGRRWQLMH ERITPNRFYW SVSGLDKEAD LVHMEVRTAD GYAHYLTCRI QECAETTRSG PFARSIDISS LVVQDEYIFI QVTIGGRASY YVSYRREAFA QIKLPKYSLP KDMHIISTDE NQVFAAVQEW NQNDTYNLYI SDTRGIYFTL AMENIKSSRG LMGNIIIELY EVAGIKGIFL ANKKVDDQVK TYITYNKGRD WRLLQAPDVD LRGSPVHCLL PFCSLHLHLQ LSENPYSSGR ISSKDTAPGL VVATGNIGSE LSYTDIGVFI SSDGGNTWRQ IFDEEYNVWF LDWGGALVAM KHTPLPVRHL WVSFDEGHSW DKYGFTLLPL FVDGALVEAG VETHIMTVFG HFSLRSEWQL VKVDYKSIFS RRCTKEDFET WHLLNQGEPC VMGERKIFKK RKPGAQCALG REYSGSVVSE PCVCADWDFE CDYGYERHGE SQCVPAFWYN PASPSKDCSL GQSYLNSTGY RRIVSNNCTD GLRDKYSAKT QLCPGKAPRG LHVVTTDGRL VAEQGHNATF IILMEEGDLQ RTNIQLDFGD GVAVSYANFS PIEDGIRHVY KSAGIFQVTA YAENNLGSDT AFLFLHVVCP VEHVHLRVPF VAIRNKDVNI SAVVWPSQLG TLTYFWWFGN STKPLITLDS SISFTFLAEG TNTITVQVAA GNALIQDTKE IAVHEYFQSQ LLSFSPNLDY HNPDIPEWRQ DIGNVIKRAL IKVTSVPEDQ ILVAVFPGLP TSAELFILPP KNLTERRKGH EGDLEQIVET LFNALNQNLV QFELKPGVQV IVYVTQLTLA PLVDSSAGHS SSAMLMLLSV VFVGLAVFLI YKFKRKIPWI NIYAQVQHDK EQEMIGSVSQ SENAPKITLS DFTEPEELLD KELDTRVIGS IATIASSEST KEIPNCTSV //