ID Q17UX2_HBV Unreviewed; 134 AA. AC Q17UX2; DT 25-JUL-2006, integrated into UniProtKB/TrEMBL. DT 25-JUL-2006, sequence version 1. DT 12-AUG-2020, entry version 54. DE SubName: Full=RNA-directed DNA polymerase {ECO:0000313|EMBL:CAK55519.1}; DE EC=2.7.7.49 {ECO:0000313|EMBL:CAK55519.1}; DE Flags: Fragment; GN Name=Pol {ECO:0000313|EMBL:CAK55519.1}; GN Synonyms=RT {ECO:0000313|EMBL:CAK55519.1}; OS Hepatitis B virus subtype ayw. OC Viruses; Hepadnaviridae; Orthohepadnavirus. OX NCBI_TaxID=10418 {ECO:0000313|EMBL:CAK55519.1}; RN [1] {ECO:0000313|EMBL:CAK55519.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=HBV-MM-KWT-13 {ECO:0000313|EMBL:CAK55519.1}; RX PubMed=20509964; RA Ali M.M., Hasan F., Ahmad S., Al-Nakib W.; RT "Comparative evaluation of INNO-LiPA HBV assay, direct DNA sequencing and RT subtractive PCR-RFLP for genotyping of clinical HBV isolates."; RL Virol. J. 7:111-111(2010). CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}. Virion CC membrane {ECO:0000256|ARBA:ARBA00004182}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AM279432; CAK55519.1; -; Genomic_DNA. DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW. DR GO; GO:0016032; P:viral process; IEA:InterPro. DR Gene3D; 3.30.70.270; -; 1. DR InterPro; IPR043502; DNA/RNA_pol_sf. DR InterPro; IPR000349; HBV_HBSAG. DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase. DR InterPro; IPR000477; RT_dom. DR Pfam; PF00078; RVT_1; 1. DR Pfam; PF00695; vMSA; 1. DR SUPFAM; SSF56672; SSF56672; 1. DR PROSITE; PS50878; RT_POL; 1. PE 4: Predicted; KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932}; KW Endonuclease {ECO:0000256|ARBA:ARBA00022759}; KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022581}; KW Hydrolase {ECO:0000256|ARBA:ARBA00022759}; KW Membrane {ECO:0000256|ARBA:ARBA00023136}; KW Nuclease {ECO:0000256|ARBA:ARBA00022722}; KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695, KW ECO:0000313|EMBL:CAK55519.1}; KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918, KW ECO:0000313|EMBL:CAK55519.1}; KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CAK55519.1}; KW Virion {ECO:0000256|ARBA:ARBA00022844}. FT DOMAIN 1..133 FT /note="Reverse transcriptase" FT /evidence="ECO:0000259|PROSITE:PS50878" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:CAK55519.1" FT NON_TER 134 FT /evidence="ECO:0000313|EMBL:CAK55519.1" SQ SEQUENCE 134 AA; 14778 MW; 8A0BDD416DD01AEA CRC64; SSTTSGPCRT CTTPAQGTSM YPSCCCTKPS DGNCTCIPIP SSWAFGKFLW EWASARFSWL SLLVPFVQWF VGLSPTCLAY SYMDDVVLGA KSVQHLESLF TAVTNFLLSL GIHLNPNKTK RWGYSLHFMG YVIG //