ID Q17UX2_HBV Unreviewed; 134 AA. AC Q17UX2; DT 25-JUL-2006, integrated into UniProtKB/TrEMBL. DT 25-JUL-2006, sequence version 1. DT 19-MAR-2014, entry version 39. DE SubName: Full=RNA-directed DNA polymerase; DE EC=2.7.7.49; DE Flags: Fragment; GN Name=Pol; Synonyms=RT; OS Hepatitis B virus subtype ayw. OC Viruses; Retro-transcribing viruses; Hepadnaviridae; OC Orthohepadnavirus. OX NCBI_TaxID=10418; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=HBV-MM-KWT-13; RX PubMed=20509964; RA Ali M.M., Hasan F., Ahmad S., Al-Nakib W.; RT "Comparative evaluation of INNO-LiPA HBV assay, direct DNA sequencing RT and subtractive PCR-RFLP for genotyping of clinical HBV isolates."; RL Virol. J. 7:111-111(2010). CC -!- SUBCELLULAR LOCATION: Virion membrane (By similarity). CC -!- SIMILARITY: Contains 1 reverse transcriptase domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AM279432; CAK55519.1; -; Genomic_DNA. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell. DR GO; GO:0003723; F:RNA binding; IEA:InterPro. DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW. DR GO; GO:0039663; P:membrane fusion involved in viral entry into host cell; IEA:UniProtKB-KW. DR GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW. DR InterPro; IPR000349; Hepvir_surfAg. DR InterPro; IPR000477; RT_dom. DR Pfam; PF00078; RVT_1; 1. DR Pfam; PF00695; vMSA; 1. DR PROSITE; PS50878; RT_POL; 1. PE 3: Inferred from homology; KW Fusion of virus membrane with host membrane; Host-virus interaction; KW Membrane; Nucleotidyltransferase; RNA-directed DNA polymerase; KW Transferase; Transmembrane; Viral attachment to host cell; KW Viral penetration into host cytoplasm; Virion; KW Virus entry into host cell. FT NON_TER 1 1 FT NON_TER 134 134 SQ SEQUENCE 134 AA; 14778 MW; 8A0BDD416DD01AEA CRC64; SSTTSGPCRT CTTPAQGTSM YPSCCCTKPS DGNCTCIPIP SSWAFGKFLW EWASARFSWL SLLVPFVQWF VGLSPTCLAY SYMDDVVLGA KSVQHLESLF TAVTNFLLSL GIHLNPNKTK RWGYSLHFMG YVIG //