ID   Q16Z05_AEDAE            Unreviewed;       166 AA.
AC   Q16Z05;
DT   25-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   25-JUL-2006, sequence version 1.
DT   10-OCT-2018, entry version 81.
DE   RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};
DE            EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};
GN   ORFNames=AAEL008369 {ECO:0000313|EMBL:EAT39863.1};
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159 {ECO:0000313|EMBL:EAT39863.1, ECO:0000313|Proteomes:UP000008820};
RN   [1] {ECO:0000313|EMBL:EAT39863.1, ECO:0000313|Proteomes:UP000008820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Liverpool/LVPib12 {ECO:0000313|Proteomes:UP000008820};
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M.,
RA   Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J.,
RA   Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P.,
RA   Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V.,
RA   Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B.,
RA   DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M.,
RA   Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H.,
RA   Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S.,
RA   Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D.,
RA   Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A.,
RA   Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D.,
RA   White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A.,
RA   Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J.,
RA   Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B.,
RA   Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
CC   -!- CATALYTIC ACTIVITY: An acylphosphate + H(2)O = a carboxylate +
CC       phosphate. {ECO:0000256|RuleBase:RU000553}.
CC   -!- SIMILARITY: Belongs to the acylphosphatase family.
CC       {ECO:0000256|RuleBase:RU004168}.
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DR   EMBL; CH477505; EAT39863.1; -; Genomic_DNA.
DR   RefSeq; XP_001653216.1; XM_001653166.1.
DR   UniGene; Aae.17744; -.
DR   ProteinModelPortal; Q16Z05; -.
DR   STRING; 7159.AAEL008369-PB; -.
DR   GeneID; 5570546; -.
DR   KEGG; aag:5570546; -.
DR   eggNOG; KOG3360; Eukaryota.
DR   eggNOG; ENOG41126ER; LUCA.
DR   HOGENOM; HOG000292688; -.
DR   InParanoid; Q16Z05; -.
DR   KO; K01512; -.
DR   OrthoDB; EOG091G0XR1; -.
DR   PhylomeDB; Q16Z05; -.
DR   Proteomes; UP000008820; Unassembled WGS sequence.
DR   GO; GO:0003998; F:acylphosphatase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR020456; Acylphosphatase.
DR   InterPro; IPR001792; Acylphosphatase-like_dom.
DR   InterPro; IPR036046; Acylphosphatase-like_dom_sf.
DR   InterPro; IPR017968; Acylphosphatase_CS.
DR   PANTHER; PTHR10029; PTHR10029; 1.
DR   Pfam; PF00708; Acylphosphatase; 1.
DR   PRINTS; PR00112; ACYLPHPHTASE.
DR   SUPFAM; SSF54975; SSF54975; 1.
DR   PROSITE; PS00150; ACYLPHOSPHATASE_1; 1.
DR   PROSITE; PS00151; ACYLPHOSPHATASE_2; 1.
DR   PROSITE; PS51160; ACYLPHOSPHATASE_3; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008820};
KW   Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00520,
KW   ECO:0000256|RuleBase:RU000553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008820}.
FT   DOMAIN       76    166       Acylphosphatase-like.
FT                                {ECO:0000259|PROSITE:PS51160}.
FT   ACT_SITE     91     91       {ECO:0000256|PROSITE-ProRule:PRU00520}.
FT   ACT_SITE    109    109       {ECO:0000256|PROSITE-ProRule:PRU00520}.
SQ   SEQUENCE   166 AA;  18488 MW;  8C54E3EF2DCB1ED5 CRC64;
     MRPRRLIEAK SPDVFIICSA LLVCYVSLAV PIVATDGVCQ SNRAGRLDTD PCLFVPESAC
     NREGKAAEEM AGKLFACDFE VFGIVQGVFF RKYTQKQATS LGLKGWCMNT RDGTVKGQME
     GEAKPVNEMK HWLQTKGSPT SRIDKAVFSE MKEISKYSFN DFSVKR
//