ID Q16591_HUMAN Unreviewed; 188 AA. AC Q16591; DT 01-NOV-1996, integrated into UniProtKB/TrEMBL. DT 01-NOV-1996, sequence version 1. DT 02-NOV-2016, entry version 54. DE SubName: Full=MYC protein {ECO:0000313|EMBL:AAA88090.1}; DE SubName: Full=Myc protein {ECO:0000313|EMBL:AAA59887.1}; DE SubName: Full=ORF 118 {ECO:0000313|EMBL:AAA88094.1}; DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAA25105.1}; GN Name=MYC {ECO:0000313|EMBL:AAA88090.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:AAA88090.1}; RN [1] {ECO:0000313|EMBL:CAA25105.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=6324175; DOI=10.1073/pnas.80.24.7476; RA Saito H., Hayday A.C., Wiman K.G., Hayward W.S., Tonegawa S.; RT "Activation of the c-myc gene by translocation: a model for RT translational control."; RL Proc. Natl. Acad. Sci. U.S.A. 80:7476-7480(1983). RN [2] {ECO:0000313|EMBL:CAA25105.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=6714223; RA Gazin C., De Dinechin S.D., Hampe A., Masson J., Martin P., RA Stehelin D., Galibert F.; RT "Nucleotide sequence of the human c-myc locus: provocative open RT reading frame within the first exon."; RL EMBO J. 3:383-387(1984). RN [3] {ECO:0000313|EMBL:AAA88090.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=3778453; DOI=10.1016/0006-291X(86)91092-2; RA Eladari M.E., Syed S.H., Guilhot S., d'Auriol L., Galibert F.; RT "On the high conservation of the human c-myc first exon."; RL Biochem. Biophys. Res. Commun. 140:313-319(1986). RN [4] {ECO:0000313|EMBL:CAA25105.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=2430795; RA Gazin C., Rigolet M., Briand J.P., Van Regenmortel M.H.V., RA Galibert F.; RT "Immunochemical detection of proteins related to the human c-myc exon RT 1."; RL EMBO J. 5:2241-2250(1986). RN [5] {ECO:0000313|EMBL:AAA88094.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Promyelocytic leukemia {ECO:0000313|EMBL:AAA88094.1}; RX PubMed=3540591; RA Bentley D.L., Groudine M.; RT "Novel promoter upstream of the human c-myc gene and regulation of c- RT myc expression in B-cell lymphomas."; RL Mol. Cell. Biol. 6:3481-3489(1986). RN [6] {ECO:0000313|EMBL:CAA25105.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=3243428; DOI=10.1016/0378-1119(88)90131-X; RA Guilhot S., Petridou B., Syed-Hussain S., Galibert F.; RT "Nucleotide sequence 3' to the human c-myc oncogene; presence of a RT long inverted repeat."; RL Gene 72:105-108(1988). RN [7] {ECO:0000313|EMBL:AAA59887.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Leukemia {ECO:0000313|EMBL:AAA59887.1}; RX PubMed=2834731; DOI=10.1073/pnas.85.9.3052; RA Finver S.N., Nishikura K., Finger L.R., Haluska F.G., Finan J., RA Nowell P.C., Croce C.M.; RT "Sequence analysis of the MYC oncogene involved in the RT t(8;14)(q24;q11) chromosome translocation in a human leukemia T-cell RT line indicates that putative regulatory regions are not altered."; RL Proc. Natl. Acad. Sci. U.S.A. 85:3052-3056(1988). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; J03253; AAA59887.1; -; Genomic_DNA. DR EMBL; M14206; AAA88090.1; -; Genomic_DNA. DR EMBL; M13930; AAA88094.1; -; mRNA. DR EMBL; X00364; CAA25105.1; -; Genomic_DNA. DR PIR; A29867; A29867. DR PIR; I79500; I79500. DR UniGene; Hs.202453; -. DR HOVERGEN; HBG053881; -. DR ChiTaRS; MYC; human. PE 2: Evidence at transcript level; SQ SEQUENCE 188 AA; 20955 MW; 677ADDDAC541477B CRC64; MRGSGRLRTP ELCCSRPPPP GPGRPWLPSC LEKGRASQRL GGKKNGGRDR AEYKSRFSGL YLTRCSNSSE RQRERAGGRL GWKSRASRAA LRASWEGRSG ANRGLRLWPS PPADPPASGP QPLPHPRNFA HSSGRALCTG TYNTRARTRL SRRGEAILPI WGHFPAAART RFSERLSLQL LRRWIFFG //