ID TR10_HUMAN STANDARD; PRT; 115 AA. AC Q15642; DT 01-NOV-1997 (REL. 35, CREATED) DT 01-NOV-1997 (REL. 35, LAST SEQUENCE UPDATE) DT 01-NOV-1997 (REL. 35, LAST ANNOTATION UPDATE) DE THYROID RECEPTOR INTERACTING PROTEIN 10 (TRIP10) (FRAGMENT). GN TRIP10. OS HOMO SAPIENS (HUMAN). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA; OC EUTHERIA; PRIMATES. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 95295737. RA LEE J.W., CHOI H.-S., GYURIS J., BRENT R., MOORE D.D.; RL MOL. ENDOCRINOL. 9:243-254(1995). CC -!- FUNCTION: THYROID RECEPTOR INTERACTING PROTEINS (TRIPS) CC SPECIFICALLY INTERACT WITH THE LIGAND BINDING DOMAIN OF THE CC THYROID RECEPTOR (TR). TRIP10 REQUIRES THE PRESENCE OF THYROID CC HORMONE FOR ITS INTERACTION. CC -!- TISSUE SPECIFICITY: EXPRESSED MOST ABUNDANTLY IN SKELETAL MUSCLE, CC HEART AND LUNG. CC -!- SIMILARITY: CONTAINS A COPY OF THE SH3 DOMAIN. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L40379; G695376; -. DR PROSITE; PS50002; SH3; 1. KW SH3 DOMAIN. FT NON_TER 1 1 FT DOMAIN 60 115 SH3. SQ SEQUENCE 115 AA; 12848 MW; E678DBE7 CRC32; KHPIICRLIH FSNSSSNSAS QDTKESSEEP PSEESQDTPI YTEFDEDFEE EPTSPIGHCV AIYHFEGSSE GTISMAEGED LSLMEEDKGD GWTRVRRKEG GEGYVPTSYL RVTLN //