ID Q14412_HUMAN Unreviewed; 42 AA. AC Q14412; DT 01-NOV-1996, integrated into UniProtKB/TrEMBL. DT 01-NOV-1996, sequence version 1. DT 02-DEC-2020, entry version 99. DE SubName: Full=A-gamma globin {ECO:0000313|EMBL:ABS32033.1}; DE SubName: Full=G-gamma globin {ECO:0000313|EMBL:AAA58610.1}; DE Flags: Fragment; GN Name=G-gamma {ECO:0000313|EMBL:AAA58610.1}; GN Synonyms=HBG1 {ECO:0000313|EMBL:ABS32033.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:AAA58610.1}; RN [1] {ECO:0000313|EMBL:AAA58610.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=6091051; DOI=10.1093/nar/12.18.7023; RA Powers P.A., Altay C., Huisman T.H., Smithies O.; RT "Two novel arrangements of the human fetal globin genes: G gamma-G gamma RT and A gamma-A gamma."; RL Nucleic Acids Res. 12:7023-7034(1984). RN [2] {ECO:0000313|EMBL:ABS32033.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=WBC {ECO:0000313|EMBL:ABS32033.1}; RC TISSUE=Whole blood {ECO:0000313|EMBL:ABS32033.1}; RA Kutlar F., Surka A.E., Li T., Nechtman J., Patel N., Kutlar A.; RT "Hb F-Port Royal; a G-gamma globin chain variant was detected on the A- RT gamma globin gene (associated with G-gamma-G-gamma gene arrangement), on a RT 7 month old baby."; RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the globin family. CC {ECO:0000256|ARBA:ARBA00008705, ECO:0000256|PROSITE-ProRule:PRU00238}. CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00238}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M32250; AAA58610.1; -; Genomic_DNA. DR EMBL; EU003441; ABS32033.1; -; Genomic_DNA. DR PIR; I78580; I78580. DR PeptideAtlas; Q14412; -. DR ChiTaRS; HBG1; human. DR GO; GO:0020037; F:heme binding; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0019825; F:oxygen binding; IEA:InterPro. DR GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW. DR Gene3D; 1.10.490.10; -; 1. DR InterPro; IPR000971; Globin. DR InterPro; IPR009050; Globin-like_sf. DR InterPro; IPR012292; Globin/Proto. DR SUPFAM; SSF46458; SSF46458; 1. DR PROSITE; PS01033; GLOBIN; 1. PE 3: Inferred from homology; KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022617}; KW Oxygen transport {ECO:0000256|ARBA:ARBA00022621}; KW Transport {ECO:0000256|ARBA:ARBA00022621}. FT DOMAIN 1..42 FT /note="GLOBIN" FT /evidence="ECO:0000259|PROSITE:PS01033" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AAA58610.1" SQ SEQUENCE 42 AA; 4528 MW; 59F315A21C11B35A CRC64; LLGNVLVTVL AIHFGKEFTP AVQASWQKMV TGVASALSSR YH //