ID SLI3_HUMAN STANDARD; PRT; 279 AA. AC Q14192; Q13229; Q13644; DT 01-NOV-1997 (REL. 35, CREATED) DT 01-NOV-1997 (REL. 35, LAST SEQUENCE UPDATE) DT 15-DEC-1998 (REL. 37, LAST ANNOTATION UPDATE) DE SKELETAL MUSCLE LIM-PROTEIN 3 (SLIM 3) (LIM-DOMAIN PROTEIN DRAL) DE (FOUR AND A HALF LIM DOMAINS PROTEIN 2) (FHL-2). GN FHL2 OR SLIM3 OR DRAL. OS HOMO SAPIENS (HUMAN). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; MAMMALIA; EUTHERIA; OC PRIMATES; CATARRHINI; HOMINIDAE; HOMO. RN [1] RP SEQUENCE FROM N.A. RC TISSUE=SKELETAL MUSCLE; RX MEDLINE; 97294674. RA GENINI M., SCHWALBE P., SCHOLL F.A., REMPPIS A., MATTEI M.-G., RA SCHAFER B.W.; RT "Subtractive cloning and characterization of DRAL, a novel LIM-domain RT protein down-regulated in rhabdomyosarcoma."; RL DNA CELL BIOL. 16:433-442(1997). RN [2] RP SEQUENCE FROM N.A. RC TISSUE=HEART; RA TSUI S., LIM N., FUNG K., WAYE M., LEE C.; RL SUBMITTED (JUN-1996) TO EMBL/GENBANK/DDBJ DATA BANKS. RN [3] RP SEQUENCE OF 127-279 FROM N.A. RC TISSUE=HEART MUSCLE; RX MEDLINE; 96354835. RA MORGAN M.J., MADGWICK A.J.A.; RT "Slim defines a novel family of LIM-proteins expressed in skeletal RT muscle."; RL BIOCHEM. BIOPHYS. RES. COMMUN. 225:632-638(1996). CC -!- TISSUE SPECIFICITY: EXPRESSED ONLY IN SKELETAL MUSCLE. CC -!- SIMILARITY: CONTAINS 4 LIM DOMAINS. THE LIM DOMAIN BINDS 2 ZINC CC IONS. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L42176; G1160932; -. DR EMBL; U29332; G1377897; -. DR EMBL; U60117; G1381812; -. DR MIM; 602633; -. DR PROSITE; PS00478; LIM_DOMAIN_1; 4. DR PROSITE; PS50023; LIM_DOMAIN_2; 5. DR PFAM; PF00412; LIM; 5. KW REPEAT; LIM MOTIF; METAL-BINDING; ZINC; ZINC-FINGER. FT ZN_FING 7 31 GATA-LIKE (POTENTIAL). FT DOMAIN 40 92 LIM 1. FT DOMAIN 101 153 LIM 2. FT DOMAIN 162 212 LIM 3. FT DOMAIN 221 275 LIM 4. FT CONFLICT 167 167 M -> G (IN REF. 1). SQ SEQUENCE 279 AA; 32196 MW; 4CA11FFB CRC32; MTERFDCHHC NESLFGKKYI LREESPYCVV CFETLFANTC EECGKPIGCD CKDLSYKDRH WHEACFHCSQ CRNSLVDKPF AAKEDQLLCT DCYSNEYSSK CQECKKTIMP GTRKMEYKGS SWHETCFICH RCQQPIGTKS FIPKDNQNFC VPCYEKQHAM QCVQCKMPIT TGGVTYREQP WHKECFVCTA CRKQLSGQRF TARDDFAYCL NCFCDLYAKK CAGCTNPISG LGGTKYISFE ERQWHNDCFN CKKCSLSLVG RGFLTERDDI LCPDCGKDI //