ID IK_HUMAN STANDARD; PRT; 162 AA. AC Q13123; DT 15-JUL-1999 (Rel. 38, Created) DT 15-JUL-1999 (Rel. 38, Last sequence update) DT 15-JUL-1999 (Rel. 38, Last annotation update) DE IK FACTOR (CYTOKINE IK). GN IK. OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; OC Eutheria; Primates; Catarrhini; Hominidae; Homo. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 95060801. RA KRIEF P., AUGERY-BOURGET Y., PLAISANCE S., MERCK M.F., ASSIER E., RA TANCHOU V., BILLARD M., BOUCHEIX C., JASMIN C., AZZARONE B.; RT "A new cytokine (IK) down-regulating HLA class II: monoclonal RT antibodies, cloning and chromosome localization."; RL Oncogene 9:3449-3456(1994). CC -!- FUNCTION: CYTOKINE THAT INHIBITS HLA CLASS II ANTIGEN INDUCTION BY CC IFN-GAMMA. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; S74221; AAB32531.1; -. DR MIM; 600549; -. KW Cytokine; Repeat. FT DOMAIN 23 60 19 X 2 AA TANDEM REPEATS OF R-[ED]. SQ SEQUENCE 162 AA; 19360 MW; 22DFF308 CRC32; MNIFEDIGDY VPSTTKTPRD KERERYRERE RDRERDRDRD RERERERDRE RERERDRERE EEKKRHSYFE KPKVDDEPMD VDKGPGSTKE LIKSINEKFA GSAGWEGTES LKKPEDKKQL GDFFGMSNSY AECYPATMDD MAVDSDEEVD YSKMDQGNKK GP //