ID T2D8_YEAST STANDARD; PRT; 206 AA. AC Q12030; DT 15-JUL-1998 (Rel. 36, Created) DT 15-JUL-1998 (Rel. 36, Last sequence update) DT 15-JUL-1998 (Rel. 36, Last annotation update) DE TRANSCRIPTION INITIATION FACTOR TFIID 23 KDA SUBUNIT (TAFII-23) DE (TAFII23) (TAFII-25) (TAFII25) (P25). GN TAF23 OR TAF25 OR YDR167W OR YD9489.02. OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=96278804; PubMed=8662725; RA Klebanow E.R., Poon D., Zhou S., Weil P.A.; RT "Isolation and characterization of TAF25, an essential yeast gene RT that encodes an RNA polymerase II-specific TATA-binding RT protein-associated factor."; RL J. Biol. Chem. 271:13706-13715(1996). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=S288C / AB972; RA Oliver K., Harris D., Barrell B.G., Rajandream M.A.; RL Submitted (JAN-1994) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: ESSENTIAL FOR VIABILITY. BONA FIDE RNA POLYMERASE II- CC SPECIFIC TAF. CC -!- FUNCTION: TFIID ACTS TO NUCLEATE THE TRANSCRIPTION COMPLEX, CC RECRUITING THE REST OF THE FACTORS THROUGH A DIRECT INTERACTION CC WITH TFIIB. THE TBP SUBUNIT OF TFIID IS SUFFICIENT FOR TATA CC ELEMENT BINDING AND TFIIB INTERACTION, AND CAN SUPPORT BASAL CC TRANSCRIPTION. CC -!- SUBUNIT: TFIID IS COMPOSED OF TATA BINDING PROTEIN (TBP) AND A CC NUMBER OF TBP-ASSOCIATED FACTORS (TAFS). CC -!- SUBCELLULAR LOCATION: NUCLEAR. CC -!- SIMILARITY: BELONGS TO THE TAF2H FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U51636; AAB07766.1; -. DR EMBL; Z47813; CAA87798.1; -. DR SGD; S0002574; TAF25. KW Transcription regulation; Nuclear protein. SQ SEQUENCE 206 AA; 23019 MW; A472CCA10DC3B495 CRC64; MDFEEDYDAE FDDNQEGQLE TPFPSVAGAD DGDNDNDDSV AENMKKKQKR EAVVDDGSEN AFGIPEFTRK DKTLEEILEM MDSTPPIIPD AVIDYYLTKN GFNVADVRVK RLLALATQKF VSDIAKDAYE YSRIRSSVAV SNANNSQARA RQLLQGQQQP GVQQISQQQH QQNEKTTASK VVLTVNDLSS AVAEYGLNIG RPDFYR //