ID T2D8_YEAST STANDARD; PRT; 206 AA. AC Q12030; DT 15-JUL-1998 (REL. 36, CREATED) DT 15-JUL-1998 (REL. 36, LAST SEQUENCE UPDATE) DT 15-JUL-1998 (REL. 36, LAST ANNOTATION UPDATE) DE TRANSCRIPTION INITIATION FACTOR TFIID 23 KD SUBUNIT (TAFII-23) DE (TAFII23) (TAFII-25) (TAFII25) (P25). GN TAF23 OR TAF25 OR YDR167W OR YD9489.02. OS SACCHAROMYCES CEREVISIAE (BAKER'S YEAST). OC EUKARYOTA; FUNGI; ASCOMYCOTINA; HEMIASCOMYCETES. RN [1] RP SEQUENCE FROM N.A. RX MEDLINE; 96278804. RA KLEBANOW E.R., POON D., ZHOU S., WEIL P.A.; RL J. BIOL. CHEM. 271:13706-13715(1996). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=S288C / AB972; RA OLIVER K., HARRIS D., BARRELL B.G., RAJANDREAM M.A.; RL SUBMITTED (JAN-1994) TO EMBL/GENBANK/DDBJ DATA BANKS. CC -!- FUNCTION: ESSENTIAL FOR VIABILITY. BONA FIDE RNA POLYMERASE II- CC SPECIFIC TAF. CC -!- FUNCTION: TFIID ACTS TO NUCLEATE THE TRANSCRIPTION COMPLEX, CC RECRUITING THE REST OF THE FACTORS THROUGH A DIRECT INTERACTION CC WITH TFIIB. THE TBP SUBUNIT OF TFIID IS SUFFICIENT FOR TATA CC ELEMENT BINDING AND TFIIB INTERACTION, AND CAN SUPPORT BASAL CC TRANSCRIPTION. CC -!- SUBUNIT: TFIID IS COMPOSED OF TATA BINDING PROTEIN (TBP) AND A CC NUMBER OF TBP-ASSOCIATED FACTORS (TAFS). CC -!- SUBCELLULAR LOCATION: NUCLEAR. CC -!- SIMILARITY: BELONGS TO THE TAF2H FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U51636; G1354326; -. DR EMBL; Z47813; G642276; -. DR SGD; L0003342; TAF23. KW TRANSCRIPTION REGULATION; NUCLEAR PROTEIN. SQ SEQUENCE 206 AA; 23019 MW; 25706D39 CRC32; MDFEEDYDAE FDDNQEGQLE TPFPSVAGAD DGDNDNDDSV AENMKKKQKR EAVVDDGSEN AFGIPEFTRK DKTLEEILEM MDSTPPIIPD AVIDYYLTKN GFNVADVRVK RLLALATQKF VSDIAKDAYE YSRIRSSVAV SNANNSQARA RQLLQGQQQP GVQQISQQQH QQNEKTTASK VVLTVNDLSS AVAEYGLNIG RPDFYR //