ID NUC1_SCHPO STANDARD; PRT; 335 AA. AC Q10480; DT 01-OCT-1996 (Rel. 34, Created) DT 01-OCT-1996 (Rel. 34, Last sequence update) DT 15-JUL-1999 (Rel. 38, Last annotation update) DE PROBABLE MITOCHONDRIAL NUCLEASE (EC 3.1.30.-). GN SPAC17C9.08. OS Schizosaccharomyces pombe (Fission yeast). OC Eukaryota; Fungi; Ascomycota; Archiascomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; OC Schizosaccharomyces. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=972; RA MURPHY L., MCDOUGALL R., JONES L., SIMPSON I., MCNEIL A., HARRIS D., RA BARRELL B.G., RAJANDREAM M.A., WALSH S.V.; RL Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: THIS ENZYME HAS BOTH RNASE AND DNASE ACTIVITY (BY CC SIMILARITY). CC -!- COFACTOR: REQUIRES MANGANESE OR MAGNESIUM (BY SIMILARITY). CC -!- SUBUNIT: HOMODIMER (BY SIMILARITY). CC -!- SUBCELLULAR LOCATION: MITOCHONDRIAL INNER MEMBRANE (POTENTIAL). CC -!- SIMILARITY: BELONGS TO THE DNA/RNA NON-SPECIFIC ENDONUCLEASES CC FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z73099; CAA97354.1; -. DR PFAM; PF01223; Endonuclease; 1. DR PROSITE; PS01070; NUCLEASE_NON_SPEC; 1. KW Hypothetical protein; Hydrolase; Nuclease; Endonuclease; Magnesium; KW Mitochondrion; Inner membrane. FT ACT_SITE 142 142 BY SIMILARITY. SQ SEQUENCE 335 AA; 38053 MW; D1E29FE8 CRC32; MSSNLIKSFG LIAIGAISGV TFTHFYYKGY QGSDVPDLTP RYTKFDSAGR ALESIYDFNA TKFFQYGIPG PVADQRVNHG YMSVFDRRTR NPFYTAETIT QESLNQRKGN RRYSEFVPDD NIPEMFQAKL GDYRGSGYDR GHQVPAADCK FSQEAMNETF YLSNMCPQVG DGFNRNYWAY FEDWCRRLTS KYGSVTIMTG PLYLPKKNER GQWEVQYRVI GNPPNVAVPT HFFKVIIAEK SGEPTSSPSV AAFVLPNKPI ADNFPLKNFA VPVEVVERAS GLEILSNVPK GNRKQLCSEV VCQLNVKEFV ESVKQKQKNQ VFLVFPVIVL YYENI //