ID Q101K9_9CHON Unreviewed; 166 AA. AC Q101K9; DT 22-AUG-2006, integrated into UniProtKB/TrEMBL. DT 22-AUG-2006, sequence version 1. DT 22-JUL-2008, entry version 15. DE RecName: Full=Cytochrome c oxidase subunit I; DE EC=1.9.3.1; DE Flags: Fragment; GN Name=COI; OS Bathyraja lindbergi (cmmander skate). OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; OC Elasmobranchii; Squalea; Hypnosqualea; Pristiorajea; Batoidea; OC Rajiformes; Rajidae; Bathyraja. OX NCBI_TaxID=341245; RN [1] RP NUCLEOTIDE SEQUENCE. RA Spies I.B., Gaichas S., Stevenson D.E., Orr J.W., Canino M.F.; RT "DNA-based identification of Alaska skates (Amblyraja, Bathyraja and RT Raja: Rajidae) using cytochrome c oxidase subunit I (coI) variation."; RL J. Fish Biol. 69:283-292(2006). CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. CO I is the CC catalytic subunit of the enzyme. Electrons originating in CC cytochrome c are transferred via the copper A center of subunit 2 CC and heme A of subunit 1 to the bimetallic center formed by heme A3 CC and copper B (By similarity). CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4 CC ferricytochrome c + 2 H(2)O. CC -!- PATHWAY: Energy metabolism; oxidative phosphorylation. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass CC membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DQ104905; AAZ91991.1; -; Genomic_DNA. DR EMBL; DQ104906; AAZ91992.1; -; Genomic_DNA. DR EMBL; DQ104907; AAZ91993.1; -; Genomic_DNA. DR EMBL; DQ104908; AAZ91994.1; -; Genomic_DNA. DR EMBL; DQ104909; AAZ91995.1; -; Genomic_DNA. DR SMR; Q101K9; 1-156. DR HOVERGEN; Q101K9; -. DR GO; GO:0016021; C:integral to membrane; IEA:InterPro. DR GO; GO:0005746; C:mitochondrial respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0005507; F:copper ion binding; IEA:UniProtKB-KW. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:EC. DR GO; GO:0009055; F:electron carrier activity; IEA:InterPro. DR GO; GO:0020037; F:heme binding; IEA:InterPro. DR GO; GO:0005506; F:iron ion binding; IEA:InterPro. DR GO; GO:0009060; P:aerobic respiration; IEA:InterPro. DR GO; GO:0006810; P:transport; IEA:UniProtKB-KW. DR InterPro; IPR000883; COX1. DR Gene3D; G3DSA:1.20.210.10; COX1; 1. DR PANTHER; PTHR10422; COX1; 1. DR Pfam; PF00115; COX1; 1. DR PRINTS; PR01165; CYCOXIDASEI. DR PROSITE; PS50855; COX1; 1. PE 3: Inferred from homology; KW Copper; Electron transport; Heme; Membrane; Mitochondrion; KW Oxidoreductase; Respiratory chain; Transmembrane; Transport. FT NON_TER 1 1 FT NON_TER 166 166 SQ SEQUENCE 166 AA; 17799 MW; AE7030D74BAC109E CRC64; LIRAELSQPG TLLGDDQIYN VIVTAHAFVM IFFMVMPIMI GGFGNWLVPL MIGSPDMAFP RMNNMSFWLL PPSFLLLLAS AGVEAGAGTG WTVYPPLAGN LAHAGASVDL TIFSLHLAGI SSILASINFI TTIINMKPPA ISQYQTPLFV WSVLVTTVLL LLALPV //