ID Q0VCQ6_BOVIN Unreviewed; 212 AA. AC Q0VCQ6; DT 05-SEP-2006, integrated into UniProtKB/TrEMBL. DT 05-SEP-2006, sequence version 1. DT 27-SEP-2017, entry version 89. DE SubName: Full=Programmed cell death 10 {ECO:0000313|EMBL:AAI20053.1, ECO:0000313|Ensembl:ENSBTAP00000042398}; GN Name=PDCD10 {ECO:0000313|EMBL:AAI20053.1, GN ECO:0000313|Ensembl:ENSBTAP00000042398}; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Bovinae; Bos. OX NCBI_TaxID=9913; RN [1] {ECO:0000313|EMBL:AAI20053.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Hereford {ECO:0000313|EMBL:AAI20053.1}; RC TISSUE=Fetal cerebellum {ECO:0000313|EMBL:AAI20053.1}; RA Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y., RA Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C., RA Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J., RA Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J., RA Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., RA Siddiqui A., Holt R., Jones S.J., Marra M.A.; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|Ensembl:ENSBTAP00000042398, ECO:0000313|Proteomes:UP000009136} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000042398, RC ECO:0000313|Proteomes:UP000009136}; RX PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42; RA Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., RA Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., RA Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.; RT "A whole-genome assembly of the domestic cow, Bos taurus."; RL Genome Biol. 10:R42.01-R42.10(2009). RN [3] {ECO:0000313|Ensembl:ENSBTAP00000042398} RP IDENTIFICATION. RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000042398}; RG Ensembl; RL Submitted (MAR-2016) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DAAA02002255; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BC120052; AAI20053.1; -; mRNA. DR RefSeq; NP_001068727.1; NM_001075259.1. DR RefSeq; XP_005201773.1; XM_005201716.3. DR RefSeq; XP_005201774.1; XM_005201717.3. DR UniGene; Bt.106635; -. DR SMR; Q0VCQ6; -. DR STRING; 9913.ENSBTAP00000042398; -. DR Ensembl; ENSBTAT00000044960; ENSBTAP00000042398; ENSBTAG00000031709. DR GeneID; 506411; -. DR KEGG; bta:506411; -. DR CTD; 11235; -. DR eggNOG; KOG4025; Eukaryota. DR eggNOG; ENOG410XTA6; LUCA. DR GeneTree; ENSGT00390000017913; -. DR HOGENOM; HOG000007888; -. DR HOVERGEN; HBG052811; -. DR KO; K18269; -. DR OMA; TMGDETP; -. DR OrthoDB; EOG091G0JQQ; -. DR TreeFam; TF105802; -. DR Proteomes; UP000009136; Chromosome 1. DR Bgee; ENSBTAG00000031709; -. DR GO; GO:0005829; C:cytosol; IEA:Ensembl. DR GO; GO:0070062; C:extracellular exosome; IEA:Ensembl. DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl. DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl. DR GO; GO:0019901; F:protein kinase binding; IEA:Ensembl. DR GO; GO:0047485; F:protein N-terminus binding; IEA:Ensembl. DR GO; GO:1990830; P:cellular response to leukemia inhibitory factor; IEA:Ensembl. DR GO; GO:0051683; P:establishment of Golgi localization; IEA:Ensembl. DR GO; GO:0090168; P:Golgi reassembly; IEA:Ensembl. DR GO; GO:0036481; P:intrinsic apoptotic signaling pathway in response to hydrogen peroxide; IEA:Ensembl. DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl. DR GO; GO:1903588; P:negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis; IEA:Ensembl. DR GO; GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IEA:Ensembl. DR GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl. DR GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl. DR GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl. DR GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl. DR GO; GO:0090316; P:positive regulation of intracellular protein transport; IEA:Ensembl. DR GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl. DR GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl. DR GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl. DR GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IEA:Ensembl. DR GO; GO:0050821; P:protein stabilization; IEA:Ensembl. DR GO; GO:0044319; P:wound healing, spreading of cells; IEA:Ensembl. DR InterPro; IPR009652; PDCD10. DR PANTHER; PTHR13250; PTHR13250; 1. PE 2: Evidence at transcript level; KW Complete proteome {ECO:0000313|Proteomes:UP000009136}; KW Reference proteome {ECO:0000313|Proteomes:UP000009136}. SQ SEQUENCE 212 AA; 24716 MW; 5AA613F709C63F56 CRC64; MRMTMEEMKN EAETTSMVSM PLYAVMYPVF NELERVNLSA AQTLRAAFIK AEKENPGLTQ DIIMKILEKK SVEVNFTESL LRMAADDVEE YMIERPEPEF QDLNEKARAL KQILSKIPDE INDRVRFLQT IKDIASAIKE LLDTVNNVFK KYQYQNRRAL EHQKKEFVKY SKSFSDTLKT YFKDGKAINV FISANRLIHQ TNLILQTFKT VA //