ID Q0PCN8_POVBK Unreviewed; 351 AA. AC Q0PCN8; DT 19-SEP-2006, integrated into UniProtKB/TrEMBL. DT 19-SEP-2006, sequence version 1. DT 29-SEP-2021, entry version 42. DE RecName: Full=Minor capsid protein {ECO:0000256|PIRNR:PIRNR003377}; GN Name=vp2 {ECO:0000313|EMBL:AUF70035.1}; OS BK polyomavirus (BKPyV) (Human polyomavirus 1). OC Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; OC Sepolyvirales; Polyomaviridae; Betapolyomavirus. OX NCBI_TaxID=1891762 {ECO:0000313|EMBL:BAF03107.1, ECO:0000313|Proteomes:UP000132816}; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] {ECO:0000313|Proteomes:UP000114154, ECO:0000313|Proteomes:UP000132816} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=FIN-10 {ECO:0000313|EMBL:BAF03107.1}, FIN-11 RC {ECO:0000313|EMBL:BAF03089.1}, FIN-13 {ECO:0000313|EMBL:BAF03083.1}, RC FIN-14 {ECO:0000313|EMBL:BAF03101.1}, and FIN-23 RC {ECO:0000313|EMBL:BAF03095.1}; RX PubMed=17030853; DOI=10.1099/vir.0.82266-0; RA Ikegaya H., Saukko P.J., Tertti R., Metsarinne K.P., Carr M.J., Crowley B., RA Sakurada K., Zheng H.-Y., Kitamura T., Yogo Y.; RT "Identification of a genomic subgroup of BK polyomavirus spread in European RT populations."; RL J. Gen. Virol. 87:3201-3208(2006). RN [2] {ECO:0000313|EMBL:BAF02937.1, ECO:0000313|Proteomes:UP000114668} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JL {ECO:0000313|EMBL:BAF02937.1}; RX PubMed=16897259; DOI=10.1007/s00239-005-0092-5; RA Nishimoto Y., Takasaka T., Hasegawa M., Zheng H.Y., Chen Q., Sugimoto C., RA Kitamura T., Yogo Y.; RT "Evolution of BK virus based on complete genome data."; RL J. Mol. Evol. 63:341-352(2006). RN [3] {ECO:0000313|EMBL:ABI94626.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=PittNP2 {ECO:0000313|EMBL:ABI94638.1}, PittVM4 RC {ECO:0000313|EMBL:ABI94650.1}, PittVM5 {ECO:0000313|EMBL:ABI94674.1}, RC PittVR3 {ECO:0000313|EMBL:ABI94626.1}, PittVR5 RC {ECO:0000313|EMBL:ABI94662.1}, and PittVR6 RC {ECO:0000313|EMBL:ABI94704.1}; RX PubMed=16940499; DOI=10.1128/JVI.00510-06; RA Sharma P.M., Gupta G., Vats A., Shapiro R., Randhawa P.; RT "Phylogenetic analysis of polyomavirus BK sequences."; RL J. Virol. 80:8869-8879(2006). RN [4] {ECO:0000313|Proteomes:UP000099017, ECO:0000313|Proteomes:UP000103015} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=J2B-13 {ECO:0000313|EMBL:BAF93371.1}, J2B-9 RC {ECO:0000313|EMBL:BAF93359.1}, J3B-3 {ECO:0000313|EMBL:BAF93377.1}, RC LAB-11 {ECO:0000313|EMBL:BAF93287.1}, LAB-14 RC {ECO:0000313|EMBL:BAF93293.1}, LAB-20 {ECO:0000313|EMBL:BAF93305.1}, RC LAB-22 {ECO:0000313|EMBL:BAF93317.1}, LAB-25 RC {ECO:0000313|EMBL:BAF93323.1}, LAB-29 {ECO:0000313|EMBL:BAF93335.1}, RC and LAB-7 {ECO:0000313|EMBL:BAF93275.1}; RX PubMed=17855530; DOI=10.1128/JVI.01018-07; RA Yogo Y., Zhong S., Suzuki M., Shibuya A., Kitamura T.; RT "Occurrence of the European subgroup of subtype I BK polyomavirus in RT Japanese-Americans suggests transmission outside the family."; RL J. Virol. 81:13254-13258(2007). RN [5] {ECO:0000313|Proteomes:UP000109992, ECO:0000313|Proteomes:UP000125417} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ESP-2 {ECO:0000313|EMBL:BAF42893.1}, ETH-4 RC {ECO:0000313|EMBL:BAF42905.1}, FNL-12 {ECO:0000313|EMBL:BAF42911.1}, RC FNL-22 {ECO:0000313|EMBL:BAF42917.1}, GBR-4 RC {ECO:0000313|EMBL:BAF42929.1}, GBR-8 {ECO:0000313|EMBL:BAF42941.1}, RC GBR-9 {ECO:0000313|EMBL:BAF42947.1}, SWE-2 RC {ECO:0000313|EMBL:BAF43013.1}, and TUR-5 RC {ECO:0000313|EMBL:BAF43019.1}; RX PubMed=17208484; DOI=10.1016/j.micinf.2006.11.008; RA Zheng H., Nishimoto Y., Chen Q., Hasegawa M., Zhong S., Ikegaya H., RA Ohno N., Sugimoto C., Takasaka T., Kitamura T., Yogo Y.; RT "Relationships between BK virus lineages and human populations."; RL Microbes Infect. 9:204-213(2007). RN [6] {ECO:0000313|Proteomes:UP000128906, ECO:0000313|Proteomes:UP000137174} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=A-23H {ECO:0000313|EMBL:BAG84438.1}, A-36H RC {ECO:0000313|EMBL:BAG84444.1}, and A-47H RC {ECO:0000313|EMBL:BAG84462.1}; RX PubMed=19088283; DOI=10.1099/vir.0.83611-0; RA Zhong S., Randhawa P.S., Ikegaya H., Chen Q., Zheng H., Suzuki M., RA Takeuchi T., Shibuya A., Kitamura T., Yogo Y.; RT "Distribution patterns of BK polyomavirus (BKV) subtypes and subgroups in RT American, European and Asian populations suggest co-migration of BKV and RT the human race."; RL J. Gen. Virol. 90:144-152(2009). RN [7] {ECO:0000313|EMBL:CBX88330.1, ECO:0000313|Proteomes:UP000133047} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Shevtsov A., Seydalina A., Gribanov O., Gorbatenko E., Momynaliev K.; RT "BK polyomavirus DNA, complete genome, isolate RU12."; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [8] {ECO:0000313|EMBL:CBX88348.1, ECO:0000313|Proteomes:UP000129175} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Shevtsov A., Seydalina A., Gribanov O., Gorbatenko E., Momynaliev K.; RT "BK polyomavirus DNA, complete genome, isolate RU16."; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [9] {ECO:0000313|EMBL:CBX88354.1, ECO:0000313|Proteomes:UP000129693} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Shevtsov A., Seydalina A., Gribanov O., Gorbatenko E., Momynaliev K.; RT "BK polyomavirus DNA, complete genome, isolate RU18."; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [10] {ECO:0000313|EMBL:CBX88360.1, ECO:0000313|Proteomes:UP000104723} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Shevtsov A., Seydalina A., Gribanov O., Gorbatenko E., Momynaliev K.; RT "BK polyomavirus DNA, complete genome, isolate RU19."; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [11] {ECO:0000313|EMBL:CBX88270.1, ECO:0000313|Proteomes:UP000103779} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Shevtsov A., Seydalina A., Gribanov O., Gorbatenko E., Momynaliev K.; RT "BK polyomavirus DNA, complete genome, isolate RU2."; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [12] {ECO:0000313|EMBL:CBX88282.1, ECO:0000313|Proteomes:UP000129100} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Shevtsov A., Seydalina A., Gribanov O., Gorbatenko E., Momynaliev K.; RT "BK polyomavirus DNA, complete genome, isolate RU4."; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [13] {ECO:0000313|EMBL:CBX88288.1, ECO:0000313|Proteomes:UP000135618} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Shevtsov A., Seydalina A., Gribanov O., Gorbatenko E., Momynaliev K.; RT "BK polyomavirus DNA, complete genome, isolate RU5."; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [14] {ECO:0000313|EMBL:CBX88294.1, ECO:0000313|Proteomes:UP000118089} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Shevtsov A., Seydalina A., Gribanov O., Gorbatenko E., Momynaliev K.; RT "BK polyomavirus DNA, complete genome, isolate RU6."; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [15] {ECO:0000313|EMBL:CBX88306.1, ECO:0000313|Proteomes:UP000173849} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Shevtsov A., Seydalina A., Gribanov O., Gorbatenko E., Momynaliev K.; RT "BK polyomavirus DNA, complete genome, isolate RU8."; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [16] {ECO:0000313|EMBL:CBX88312.1, ECO:0000313|Proteomes:UP000125873} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Shevtsov A., Seydalina A., Gribanov O., Gorbatenko E., Momynaliev K.; RT "BK polyomavirus DNA, complete genome, isolate RU9."; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [17] {ECO:0000313|Proteomes:UP000097691, ECO:0000313|Proteomes:UP000128294} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SJH-LG-253 {ECO:0000313|EMBL:AEO89579.1}, SJH-LG-305 RC {ECO:0000313|EMBL:AEO89591.1}, and SJH-LG-308 RC {ECO:0000313|EMBL:AEO89603.1}; RX PubMed=22585720; DOI=10.1002/jmv.23240; RA Drew R.J., Walsh A., Laoi B.N., Crowley B.; RT "Phylogenetic analysis of the complete genome of 11 BKV isolates obtained RT from allogenic stem cell transplant recipients in Ireland."; RL J. Med. Virol. 84:1037-1048(2012). RN [18] {ECO:0000313|EMBL:AUF70035.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=BKV {ECO:0000313|EMBL:AUF70035.1}; RA Boijout H., Lafon M.-E., Bissau R.K.; RT "Complete genomes of two BKV from Bordeaux, France."; RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases. RN [19] {ECO:0000313|EMBL:QTJ14932.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=UBK029 {ECO:0000313|EMBL:QTJ14932.1}, UBK065 RC {ECO:0000313|EMBL:QTJ14968.1}, UBK077 {ECO:0000313|EMBL:QTJ14980.1}, RC UBK086 {ECO:0000313|EMBL:QTJ14986.1}, UBK088_new RC {ECO:0000313|EMBL:QTJ14992.1}, UBK140 {ECO:0000313|EMBL:QTJ15022.1}, RC UBK143 {ECO:0000313|EMBL:QTJ15028.1}, UBK174 RC {ECO:0000313|EMBL:QTJ15046.1}, UBK272 {ECO:0000313|EMBL:QTJ15100.1}, RC and UBK289 {ECO:0000313|EMBL:QTJ15124.1}; RA Addetia A., Phung Q., Greninger A.; RT "Defective polyomavirus genomes in clinical urine samples."; RL Submitted (FEB-2021) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane CC {ECO:0000256|ARBA:ARBA00004586}. Host endoplasmic reticulum membrane CC {ECO:0000256|ARBA:ARBA00004625}. Membrane CC {ECO:0000256|ARBA:ARBA00004370}. Virion CC {ECO:0000256|ARBA:ARBA00004328}. CC -!- SIMILARITY: Belongs to the polyomaviruses capsid protein VP2 family. CC {ECO:0000256|ARBA:ARBA00006444, ECO:0000256|PIRNR:PIRNR003377}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DQ989797; ABI94626.1; -; Genomic_DNA. DR EMBL; DQ989799; ABI94638.1; -; Genomic_DNA. DR EMBL; DQ989801; ABI94650.1; -; Genomic_DNA. DR EMBL; DQ989803; ABI94662.1; -; Genomic_DNA. DR EMBL; DQ989805; ABI94674.1; -; Genomic_DNA. DR EMBL; DQ989810; ABI94704.1; -; Genomic_DNA. DR EMBL; JN192434; AEO89579.1; -; Genomic_DNA. DR EMBL; JN192436; AEO89591.1; -; Genomic_DNA. DR EMBL; JN192438; AEO89603.1; -; Genomic_DNA. DR EMBL; MF627830; AUF70035.1; -; Genomic_DNA. DR EMBL; AB211370; BAF02937.1; -; Genomic_DNA. DR EMBL; AB260028; BAF03083.1; -; Genomic_DNA. DR EMBL; AB260029; BAF03089.1; -; Genomic_DNA. DR EMBL; AB260030; BAF03095.1; -; Genomic_DNA. DR EMBL; AB260031; BAF03101.1; -; Genomic_DNA. DR EMBL; AB260032; BAF03107.1; -; Genomic_DNA. DR EMBL; AB263915; BAF42893.1; -; Genomic_DNA. DR EMBL; AB263917; BAF42905.1; -; Genomic_DNA. DR EMBL; AB263918; BAF42911.1; -; Genomic_DNA. DR EMBL; AB263919; BAF42917.1; -; Genomic_DNA. DR EMBL; AB263921; BAF42929.1; -; Genomic_DNA. DR EMBL; AB263923; BAF42941.1; -; Genomic_DNA. DR EMBL; AB263924; BAF42947.1; -; Genomic_DNA. DR EMBL; AB263935; BAF43013.1; -; Genomic_DNA. DR EMBL; AB263936; BAF43019.1; -; Genomic_DNA. DR EMBL; AB301086; BAF93275.1; -; Genomic_DNA. DR EMBL; AB301088; BAF93287.1; -; Genomic_DNA. DR EMBL; AB301089; BAF93293.1; -; Genomic_DNA. DR EMBL; AB301091; BAF93305.1; -; Genomic_DNA. DR EMBL; AB301093; BAF93317.1; -; Genomic_DNA. DR EMBL; AB301094; BAF93323.1; -; Genomic_DNA. DR EMBL; AB301096; BAF93335.1; -; Genomic_DNA. DR EMBL; AB301100; BAF93359.1; -; Genomic_DNA. DR EMBL; AB301102; BAF93371.1; -; Genomic_DNA. DR EMBL; AB301103; BAF93377.1; -; Genomic_DNA. DR EMBL; AB369087; BAG84438.1; -; Genomic_DNA. DR EMBL; AB369088; BAG84444.1; -; Genomic_DNA. DR EMBL; AB369091; BAG84462.1; -; Genomic_DNA. DR EMBL; FR720308; CBX88270.1; -; Genomic_DNA. DR EMBL; FR720310; CBX88282.1; -; Genomic_DNA. DR EMBL; FR720311; CBX88288.1; -; Genomic_DNA. DR EMBL; FR720312; CBX88294.1; -; Genomic_DNA. DR EMBL; FR720314; CBX88306.1; -; Genomic_DNA. DR EMBL; FR720315; CBX88312.1; -; Genomic_DNA. DR EMBL; FR720318; CBX88330.1; -; Genomic_DNA. DR EMBL; FR720321; CBX88348.1; -; Genomic_DNA. DR EMBL; FR720322; CBX88354.1; -; Genomic_DNA. DR EMBL; FR720323; CBX88360.1; -; Genomic_DNA. DR EMBL; MW587959; QTJ14932.1; -; Genomic_DNA. DR EMBL; MW587965; QTJ14968.1; -; Genomic_DNA. DR EMBL; MW587967; QTJ14980.1; -; Genomic_DNA. DR EMBL; MW587968; QTJ14986.1; -; Genomic_DNA. DR EMBL; MW587969; QTJ14992.1; -; Genomic_DNA. DR EMBL; MW587974; QTJ15022.1; -; Genomic_DNA. DR EMBL; MW587975; QTJ15028.1; -; Genomic_DNA. DR EMBL; MW587978; QTJ15046.1; -; Genomic_DNA. DR EMBL; MW587987; QTJ15100.1; -; Genomic_DNA. DR EMBL; MW587991; QTJ15124.1; -; Genomic_DNA. DR Proteomes; UP000097691; Genome. DR Proteomes; UP000099017; Genome. DR Proteomes; UP000103015; Genome. DR Proteomes; UP000103779; Genome. DR Proteomes; UP000104723; Genome. DR Proteomes; UP000109568; Genome. DR Proteomes; UP000109992; Genome. DR Proteomes; UP000114154; Genome. DR Proteomes; UP000114668; Genome. DR Proteomes; UP000114751; Genome. DR Proteomes; UP000118089; Genome. DR Proteomes; UP000119557; Genome. DR Proteomes; UP000125417; Genome. DR Proteomes; UP000125873; Genome. DR Proteomes; UP000128294; Genome. DR Proteomes; UP000128906; Genome. DR Proteomes; UP000129100; Genome. DR Proteomes; UP000129175; Genome. DR Proteomes; UP000129693; Genome. DR Proteomes; UP000131657; Genome. DR Proteomes; UP000132816; Genome. DR Proteomes; UP000133047; Genome. DR Proteomes; UP000135618; Genome. DR Proteomes; UP000137174; Genome. DR Proteomes; UP000141196; Genome. DR Proteomes; UP000141860; Genome. DR Proteomes; UP000142034; Genome. DR Proteomes; UP000142151; Genome. DR Proteomes; UP000146760; Genome. DR Proteomes; UP000149192; Genome. DR Proteomes; UP000149967; Genome. DR Proteomes; UP000151638; Genome. DR Proteomes; UP000153508; Genome. DR Proteomes; UP000157269; Genome. DR Proteomes; UP000159188; Genome. DR Proteomes; UP000160961; Genome. DR Proteomes; UP000163031; Genome. DR Proteomes; UP000166126; Genome. DR Proteomes; UP000167368; Genome. DR Proteomes; UP000171439; Genome. DR Proteomes; UP000173849; Genome. DR GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell. DR GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule. DR GO; GO:0005198; F:structural molecule activity; IEA:UniProtKB-UniRule. DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW. DR GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW. DR InterPro; IPR001070; Polyoma_coat_VP2. DR Pfam; PF00761; Polyoma_coat2; 1. DR PIRSF; PIRSF003377; Polyoma_coat2; 1. PE 3: Inferred from homology; KW Capsid protein {ECO:0000256|PIRNR:PIRNR003377}; KW Host endoplasmic reticulum {ECO:0000256|ARBA:ARBA00023184}; KW Host membrane {ECO:0000256|ARBA:ARBA00022870}; KW Membrane {ECO:0000256|ARBA:ARBA00023136}; KW Virion {ECO:0000256|PIRNR:PIRNR003377}. FT REGION 313..351 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 337..351 FT /note="Basic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 351 AA; 38360 MW; 9BC4BB1793D632C9 CRC64; MGAALALLGD LVASVSEAAA ATGFSVAEIA AGEAAAAIEV QIASLATVEG ITSTSEAIAA IGLTPQTYAV IAGAPGAIAG FAALIQTVTG ISSLAQVGYR FFSDWDHKVS TVGLYQQSGM ALELFNPDEY YDILFPGVNT FVNNIQYLDP RHWGPSLFAT ISQALWHVIR DDIPAITSQE LQRRTERFFR DSLARFLEET TWTIVNAPIN FYNYIQEYYS DLSPIRPSMV RQVAEREGTR VHFGHTYSID DADSIEEVTQ RMDLRNQQTV HSGEFIEKTI APGGANQRTA PQWMLPLLLG LYGTVTPALE AYEDGPNKKK RRVSRGSSQK AKGTRASAKT TNKRRSRSSR S //