ID   Q0P4I5_XENTR            Unreviewed;       350 AA.
AC   Q0P4I5; F6VVS6;
DT   19-SEP-2006, integrated into UniProtKB/TrEMBL.
DT   19-SEP-2006, sequence version 1.
DT   27-NOV-2024, entry version 96.
DE   SubName: Full=G protein-coupled receptor 23 {ECO:0000313|EMBL:AAI22064.1};
DE   SubName: Full=Lysophosphatidic acid receptor 4 {ECO:0000313|RefSeq:NP_001072847.1};
GN   Name=lpar4 {ECO:0000313|RefSeq:NP_001072847.1,
GN   ECO:0000313|Xenbase:XB-GENE-989373};
GN   Synonyms=gpr23 {ECO:0000313|EMBL:AAI22064.1,
GN   ECO:0000313|RefSeq:NP_001072847.1}, lpa4
GN   {ECO:0000313|RefSeq:NP_001072847.1};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI22064.1};
RN   [1] {ECO:0000313|RefSeq:NP_001072847.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12454917; DOI=10.1002/dvdy.10174;
RA   Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA   Richardson P.;
RT   "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT   initiative.";
RL   Dev. Dyn. 225:384-391(2002).
RN   [2] {ECO:0000313|EMBL:AAI22064.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6 {ECO:0000313|EMBL:AAI22064.1};
RC   TISSUE=Heart {ECO:0000313|EMBL:AAI22064.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|RefSeq:NP_001072847.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (AUG-2024) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688}.
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DR   EMBL; BC122063; AAI22064.1; -; mRNA.
DR   RefSeq; NP_001072847.1; NM_001079379.1.
DR   STRING; 8364.ENSXETP00000042569; -.
DR   PaxDb; 8364-ENSXETP00000039948; -.
DR   DNASU; 780308; -.
DR   GeneID; 780308; -.
DR   KEGG; xtr:780308; -.
DR   AGR; Xenbase:XB-GENE-989373; -.
DR   CTD; 2846; -.
DR   Xenbase; XB-GENE-989373; lpar4.
DR   OMA; FRMKMRN; -.
DR   OrthoDB; 5351855at2759; -.
DR   Reactome; R-XTR-416476; G alpha (q) signalling events.
DR   Reactome; R-XTR-417957; P2Y receptors.
DR   Proteomes; UP000008143; Chromosome 8.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   CDD; cd15155; 7tmA_LPAR4; 1.
DR   FunFam; 1.20.1070.10:FF:000017; lysophosphatidic acid receptor 4; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   PANTHER; PTHR24232; G-PROTEIN COUPLED RECEPTOR; 1.
DR   PANTHER; PTHR24232:SF41; LYSOPHOSPHATIDIC ACID RECEPTOR 4; 1.
DR   Pfam; PF00001; 7tm_1; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR01067; P2Y5ORPHANR.
DR   SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   2: Evidence at transcript level;
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|RuleBase:RU000688, ECO:0000313|EMBL:AAI22064.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW   Transducer {ECO:0000256|RuleBase:RU000688};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000688};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        55..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        183..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        227..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        271..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          35..290
FT                   /note="G-protein coupled receptors family 1 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50262"
SQ   SEQUENCE   350 AA;  39542 MW;  831AF19BA6BD27B3 CRC64;
     MGNESNNSTC LIDDSFKYNL YGAVYSVVFI FGLITNCASL FVFCFKMRMQ NETAIFMTNL
     AVSDLLFVFT LPFKIFYNFN RHWPFGDSLC KISGTAFLTN IYGSMLFLTC ISVDRFLAIV
     YPFRSRTIRT RKNSAIVCAC VWIIVLSGGI SASLFSTTNV SNTSTTCFEG FSKSIWKTYL
     SKITIFIEVV GFIIPLLLNL TCSSLVLRTL RKPATLCQIG TNKEKVLKMI VVHVAIFVVC
     FVPFNSILFL YALVRSQAIS NCAVERFART MYPITLCIAT MNCCFDPFVY YFTSKSFQKS
     FNINPIIKMD TLFKIDSATK IALPVTQEEL TEQMNINNGG ELMSEANYKD
//