ID   Q0IH30_XENLA            Unreviewed;       466 AA.
AC   Q0IH30;
DT   03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2006, sequence version 1.
DT   28-JUN-2023, entry version 60.
DE   SubName: Full=Carkl protein {ECO:0000313|EMBL:AAI23344.1};
DE   SubName: Full=Sedoheptulokinase S homeolog {ECO:0000313|RefSeq:NP_001090399.1};
DE            EC=2.7.1.14 {ECO:0000313|RefSeq:NP_001090399.1};
GN   Name=shpk.S {ECO:0000313|RefSeq:NP_001090399.1,
GN   ECO:0000313|Xenbase:XB-GENE-991312};
GN   Synonyms=carkl {ECO:0000313|EMBL:AAI23344.1,
GN   ECO:0000313|RefSeq:NP_001090399.1}, shpk
GN   {ECO:0000313|RefSeq:NP_001090399.1,
GN   ECO:0000313|Xenbase:XB-GENE-991312};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355 {ECO:0000313|EMBL:AAI23344.1};
RN   [1] {ECO:0000313|RefSeq:NP_001090399.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12454917; DOI=10.1002/dvdy.10174;
RA   Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA   Richardson P.;
RT   "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT   initiative.";
RL   Dev. Dyn. 225:384-391(2002).
RN   [2] {ECO:0000313|EMBL:AAI23344.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary {ECO:0000313|EMBL:AAI23344.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|RefSeq:NP_001090399.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (MAR-2023) to UniProtKB.
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DR   EMBL; BC123343; AAI23344.1; -; mRNA.
DR   RefSeq; NP_001090399.1; NM_001096930.1.
DR   DNASU; 779311; -.
DR   GeneID; 779311; -.
DR   KEGG; xla:779311; -.
DR   CTD; 779311; -.
DR   Xenbase; XB-GENE-991312; shpk.S.
DR   OrthoDB; 70798at2759; -.
DR   Proteomes; UP000186698; Chromosome 2S.
DR   Bgee; 779311; Expressed in muscle tissue and 19 other tissues.
DR   GO; GO:0050277; F:sedoheptulokinase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd07777; FGGY_SHK_like; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018484; Carb_kinase_FGGY_N.
DR   InterPro; IPR042027; SHK.
DR   PANTHER; PTHR10196:SF67; SEDOHEPTULOKINASE; 1.
DR   PANTHER; PTHR10196; SUGAR KINASE; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   2: Evidence at transcript level;
KW   Reference proteome {ECO:0000313|Proteomes:UP000186698}.
FT   DOMAIN          9..257
FT                   /note="Carbohydrate kinase FGGY N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00370"
SQ   SEQUENCE   466 AA;  50707 MW;  90781475724225AD CRC64;
     MESKASRLVL GLDVGTSSVK AALLDAASGN VVHSQSRETR AAVQSECGPQ GKEQDVVLIM
     RTLNDCVSSL PKERLKEVVR IGVSGQMHGV MFWKTNQGCH WINSGNLRVF EPRDTSYLIT
     WEDGRCSMDF LASLPQPQSH LSLATGFGCA TIFWYLKNRP DFLDSYDAAG TIQDYVVAML
     CGLQRPQMSV HNAASWGYFN ARSKTWNTDI LHGAGFPVFL LPDVVNAGCV VGKASYEWCG
     IHQGTEVGVA LGDFQCSVYS SATESTDAVL NISTSAQLTF SMAEGFQPED RPSPGESVAY
     FPYFNDRYLA VAASLNGGNV LASFITMLSD WIAEFGLDIP ASTLYTRVIT AGLSQHETHL
     NINPTLFGER HTPDILASVT NIMAAELSLG HVTRALCRGI VQNLHSMLPS SRLQESGVKR
     LIGSGSALSR NEVLKQEVEK IFPFPILYGK DTDSALGAAM VMAKQW
//