ID Q0E8S4_DROME Unreviewed; 1019 AA. AC Q0E8S4; DT 17-OCT-2006, integrated into UniProtKB/TrEMBL. DT 17-OCT-2006, sequence version 1. DT 16-NOV-2011, entry version 48. DE SubName: Full=Sema-1a, isoform B; GN Name=Sema-1a; ORFNames=Dmel_CG18405; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX MEDLINE=20196006; PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22426069; PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). CC -!- SIMILARITY: Contains 1 Sema domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014134; AAN10677.2; -; Genomic_DNA. DR RefSeq; NP_001188731.1; NM_001201802.1. DR RefSeq; NP_609243.3; NM_135399.3. DR ProteinModelPortal; Q0E8S4; -. DR SMR; Q0E8S4; 93-600. DR STRING; Q0E8S4; -. DR PRIDE; Q0E8S4; -. DR GeneID; 34192; -. DR KEGG; dme:Dmel_CG18405; -. DR UCSC; CG18405-RB; d. melanogaster. DR CTD; 34192; -. DR FlyBase; FBgn0011259; Sema-1a. DR GeneTree; EMGT00050000006041; -. DR PhylomeDB; Q0E8S4; -. DR NextBio; 787331; -. DR Bgee; Q0E8S4; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0004872; F:receptor activity; IEA:InterPro. DR GO; GO:0007275; P:multicellular organismal development; IEA:InterPro. DR InterPro; IPR003659; Plexin-like. DR InterPro; IPR016201; Plexin-like_fold. DR InterPro; IPR002165; Plexin_repeat. DR InterPro; IPR001627; Semaphorin/CD100_Ag. DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom. DR Gene3D; G3DSA:2.130.10.10; WD40/YVTN_repeat-like; 1. DR KO; K06842; -. DR Pfam; PF01437; PSI; 1. DR Pfam; PF01403; Sema; 1. DR SMART; SM00423; PSI; 1. DR SMART; SM00630; Sema; 1. DR SUPFAM; SSF103575; Plexin-like_fold; 1. DR SUPFAM; SSF101912; Sema; 1. DR PROSITE; PS51004; SEMA; 1. PE 4: Predicted; KW Complete proteome; Membrane; Reference proteome; Transmembrane; KW Transmembrane helix. SQ SEQUENCE 1019 AA; 114592 MW; 44519DA6902DAC45 CRC64; MLNSHNTNHN NNSASNSNYN KGHKMHLKSA TAKATIMKHK LSKFYGYGWM QVFLLLTVLV IGNQSAWQEN IRPKLYVELG PEDVLKFVGN ESVVDHFKLV TKDGNSLLIG ARNTVFNLSI HDLVEQQRLV WTSPEDDTKM CLVKGKDEEA CQNYIRIMVV PSPGRLFVCG TNSFRPMCNT YIISDSNYTL EATKNGQAVC PYDPRHNSTS VLADNELYSG TVADFSGSDP IIYREPLQTE QYDSLSLNAP NFVSSFTQGD FVYFFFRETA VEFINCGKAI YSRVARVCKW DKGGPHRFRN RWTSFLKSRL NCSIPGDYPF YFNEIQSASN LVEGQYGSMS SKLIYGVFNT PSNSIPGSAV CAFALQDIAD TFEGQFKEQT GINSNWLPVN NAKVPDPRPG SCHNDSRALP DPTLNFIKTH SLMDENVPAF FSQPILVRTS TIYRFTQIAV DAQIKTPGGK TYDVIFVGTD HGKIIKSVNA ESADSADKVT SVVIEEIDVL TKSEPIRNLE IVRTMQYDQP KDGSYDDGKL IIVTDSQVVA IQLHRCHNDK ITSCSECVAL QDPYCAWDKI AGKCRSHGAP RWLEENYFYQ NVATGQHAAC PSGKINSKDA NAGEQKGFRN DMDLLDSRRQ SKDQEIIDNI DKNFEDIINA QYTVETLVMA VLAGSIFSLL VGFFTGYFCG RRCHKDEDDN LPYPDTEYEY FEQRQNVNSF PSSCRIQQEP KLLPQVEEVT YAEPVLLPQP PPPNKMHSPK NTLRKPPMHQ MHQGPNSETL FQFQPDGYNT QQSYRGRDNF GTLRSHQVMA SPAQSAIPRP TRFANRQRQR FLQPLFDRCV IETQPRARSP MIGRTYAKSM PVTPVQPQSP LAETPSYELY ERHSDAATFH FGDEDDDDDD EHDHEDTSSL AMITPPPPYD TPHLIASPPL PPPRRFRFGN RELFSMSPAG GGATPTASAG QRGSSAITPT KLSAAAAAMF AAPQMATQLN RKWAHLQRKR RRRNSSSGDS KELDKLVLQS VDWDENEMY //