ID CSLE2_ORYSJ Reviewed; 745 AA. AC Q0DXZ1; B7ERT8; Q944E3; DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot. DT 17-OCT-2006, sequence version 1. DT 25-MAY-2022, entry version 88. DE RecName: Full=Cellulose synthase-like protein E2; DE EC=2.4.1.-; DE AltName: Full=OsCslE2; GN Name=CSLE2; OrderedLocusNames=Os02g0725300, LOC_Os02g49332; OS Oryza sativa subsp. japonica (Rice). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa. OX NCBI_TaxID=39947; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX PubMed=11842136; DOI=10.1104/pp.010875; RA Hazen S.P., Scott-Craig J.S., Walton J.D.; RT "Cellulose synthase-like genes of rice."; RL Plant Physiol. 128:336-340(2002). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Nipponbare; RX PubMed=16100779; DOI=10.1038/nature03895; RG International rice genome sequencing project (IRGSP); RT "The map-based sequence of the rice genome."; RL Nature 436:793-800(2005). RN [3] RP GENOME REANNOTATION. RC STRAIN=cv. Nipponbare; RX PubMed=18089549; DOI=10.1093/nar/gkm978; RG The rice annotation project (RAP); RT "The rice annotation project database (RAP-DB): 2008 update."; RL Nucleic Acids Res. 36:D1028-D1033(2008). RN [4] RP GENOME REANNOTATION. RC STRAIN=cv. Nipponbare; RX PubMed=24280374; DOI=10.1186/1939-8433-6-4; RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R., RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L., RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H., RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.; RT "Improvement of the Oryza sativa Nipponbare reference genome using next RT generation sequence and optical map data."; RL Rice 6:4-4(2013). RN [5] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=cv. Nipponbare; RX PubMed=12869764; DOI=10.1126/science.1081288; RG The rice full-length cDNA consortium; RT "Collection, mapping, and annotation of over 28,000 cDNA clones from RT japonica rice."; RL Science 301:376-379(2003). CC -!- FUNCTION: Thought to be a Golgi-localized beta-glycan synthase that CC polymerize the backbones of noncellulosic polysaccharides CC (hemicelluloses) of plant cell wall. CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi- CC pass membrane protein {ECO:0000305}. CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant CC cellulose synthase-like E subfamily. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF432501; AAL25130.1; -; Genomic_DNA. DR EMBL; AP008208; BAF09897.1; -; Genomic_DNA. DR EMBL; AP014958; BAS80689.1; -; Genomic_DNA. DR EMBL; AK101487; BAG95085.1; -; mRNA. DR RefSeq; XP_015625192.1; XM_015769706.1. DR RefSeq; XP_015625193.1; XM_015769707.1. DR AlphaFoldDB; Q0DXZ1; -. DR SMR; Q0DXZ1; -. DR STRING; 4530.OS02T0725300-01; -. DR CAZy; GT2; Glycosyltransferase Family 2. DR PaxDb; Q0DXZ1; -. DR PRIDE; Q0DXZ1; -. DR EnsemblPlants; Os02t0725300-01; Os02t0725300-01; Os02g0725300. DR GeneID; 4330583; -. DR Gramene; Os02t0725300-01; Os02t0725300-01; Os02g0725300. DR KEGG; osa:4330583; -. DR eggNOG; ENOG502QS7H; Eukaryota. DR HOGENOM; CLU_001418_3_3_1; -. DR InParanoid; Q0DXZ1; -. DR OMA; KQHHFKA; -. DR OrthoDB; 679241at2759; -. DR Proteomes; UP000000763; Chromosome 2. DR Proteomes; UP000059680; Chromosome 2. DR ExpressionAtlas; Q0DXZ1; baseline and differential. DR Genevisible; Q0DXZ1; OS. DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central. DR GO; GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:InterPro. DR GO; GO:0051753; F:mannan synthase activity; IBA:GO_Central. DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW. DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:InterPro. DR GO; GO:0009833; P:plant-type primary cell wall biogenesis; IBA:GO_Central. DR Gene3D; 3.90.550.10; -; 1. DR InterPro; IPR005150; Cellulose_synth. DR InterPro; IPR029044; Nucleotide-diphossugar_trans. DR Pfam; PF03552; Cellulose_synt; 2. PE 2: Evidence at transcript level; KW Cell wall biogenesis/degradation; Glycosyltransferase; Golgi apparatus; KW Membrane; Reference proteome; Transferase; Transmembrane; KW Transmembrane helix. FT CHAIN 1..745 FT /note="Cellulose synthase-like protein E2" FT /id="PRO_0000319399" FT TRANSMEM 29..49 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 66..86 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 541..561 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 568..588 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 658..678 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 686..706 FT /note="Helical" FT /evidence="ECO:0000255" FT TRANSMEM 723..743 FT /note="Helical" FT /evidence="ECO:0000255" FT REGION 1..20 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT ACT_SITE 155 FT /evidence="ECO:0000255" FT ACT_SITE 458 FT /evidence="ECO:0000255" FT CONFLICT 686 FT /note="G -> S (in Ref. 1; AAL25130)" FT /evidence="ECO:0000305" SQ SEQUENCE 745 AA; 83646 MW; 422048BAF1CCE2DB CRC64; MAGSGGGVVS GGRQRGPPLF ATEKPGRMAM AAYRVSAATV FAGVLLIWLY RATHLPPGGG DGVRRWAWLG MLAAELWFGF YWVLTLSVRW CPVYRRTFKD RLAQSYSEDE LPSVDIFVCT ADPTAEPPML VISTVLSVMA YDYLPEKLNI YLSDDAGSVL TFYVLCEASE FAKHWIPFCK KYKVEPRSPA AYFAKVASPP DGCGPKEWFT MKELYKDMTD RVNSVVNSGR IPEVPRCHSR GFSQWNENFT SSDHPSIVQI LIDSNKQKAV DIDGNALPTL VYMAREKKPQ KQHHFKAGSL NALIRVSSVI SNSPIIMNVD CDMYSNNSES IRDALCFFLD EEQGQDIGFV QYPQNFENVV HNDIYGHPIN VVNELDHPCL DGWGGMCYYG TGCFHRREAL CGRIYSQEYK EDWTRVAGRT EDANELEEMG RSLVTCTYEH NTIWGIEKGV RYGCPLEDVT TGLQIQCRGW RSVYYNPKRK GFLGMTPTSL GQILVLYKRW TEGFLQISLS RYSPFLLGHG KIKLGLQMGY SVCGFWAVNS FPTLYYVTIP SLCFLNGISL FPEKTSPWFI PFAYVMVAAY SCSLAESLQC GDSAVEWWNA QRMWLIRRIT SYLLATIDTF RRILGISESG FNLTVKVTDL QALERYKKGM MEFGSFSAMF VILTTVALLN LACMVLGISR VLLQEGPGGL ETLFLQAVLC VLIVAINSPV YEALFLRRDK GSLPASVARV SICFVLPLCI LSICK //