ID Q09H18_MACMU Unreviewed; 182 AA. AC Q09H18; DT 17-OCT-2006, integrated into UniProtKB/TrEMBL. DT 17-OCT-2006, sequence version 1. DT 11-MAY-2016, entry version 69. DE SubName: Full=Tumor necrosis factor alpha {ECO:0000313|EMBL:ABI63795.1}; DE Flags: Fragment; GN Name=TNF-alpha {ECO:0000313|EMBL:ABI63795.1}; OS Macaca mulatta (Rhesus macaque). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. OX NCBI_TaxID=9544 {ECO:0000313|EMBL:ABI63795.1}; RN [1] {ECO:0000313|EMBL:ABI63795.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=95027 {ECO:0000313|EMBL:ABI63789.1}, and 95114 RC {ECO:0000313|EMBL:ABI63795.1}; RX PubMed=17106666; DOI=10.1007/s00251-006-0166-6; RA Weiler A., May G.E., Qi Y., Wilson N., Watkins D.I.; RT "Polymorphisms in eight host genes associated with control of HIV RT replication do not mediate elite control of viral replication in SIV- RT infected Indian rhesus macaques."; RL Immunogenetics 58:1003-1009(2006). CC -!- SIMILARITY: Belongs to the tumor necrosis factor family. CC {ECO:0000256|SAAS:SAAS00562263}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DQ902456; ABI63789.1; -; mRNA. DR EMBL; DQ902462; ABI63795.1; -; mRNA. DR UniGene; Mmu.3364; -. DR STRING; 9544.ENSMMUP00000011594; -. DR eggNOG; ENOG410ISAN; Eukaryota. DR eggNOG; ENOG410YQC4; LUCA. DR HOVERGEN; HBG012516; -. DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW. DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW. DR GO; GO:0006955; P:immune response; IEA:InterPro. DR Gene3D; 2.60.120.40; -; 1. DR InterPro; IPR006053; TNF. DR InterPro; IPR002959; TNF_alpha. DR InterPro; IPR021184; TNF_CS. DR InterPro; IPR006052; TNF_dom. DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom. DR PANTHER; PTHR11471:SF23; PTHR11471:SF23; 1. DR Pfam; PF00229; TNF; 1. DR PRINTS; PR01234; TNECROSISFCT. DR PRINTS; PR01235; TNFALPHA. DR SMART; SM00207; TNF; 1. DR SUPFAM; SSF49842; SSF49842; 1. DR PROSITE; PS00251; TNF_1; 1. DR PROSITE; PS50049; TNF_2; 1. PE 2: Evidence at transcript level; KW Cytokine {ECO:0000256|SAAS:SAAS00562264}; KW Membrane {ECO:0000256|SAAS:SAAS00449662}; KW Signal {ECO:0000256|SAM:SignalP}. FT SIGNAL 1 23 {ECO:0000256|SAM:SignalP}. FT CHAIN 24 182 {ECO:0000256|SAM:SignalP}. FT /FTId=PRO_5004167551. FT DOMAIN 54 182 TNF_2. {ECO:0000259|PROSITE:PS50049}. FT NON_TER 1 1 {ECO:0000313|EMBL:ABI63795.1}. FT NON_TER 182 182 {ECO:0000313|EMBL:ABI63795.1}. SQ SEQUENCE 182 AA; 19957 MW; C0DDC5B18CA83FA8 CRC64; FSFLLVAGAT TLFCLLHFGV IGPQREEFPK DPSLISPLAQ AVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELTDNQLV VPSEGLYLIY SQVLFKGQGC PSNHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINLP DY //