ID GAB3_DROME STANDARD; PRT; 496 AA. AC Q08832; DT 01-FEB-1995 (REL. 31, CREATED) DT 01-FEB-1995 (REL. 31, LAST SEQUENCE UPDATE) DT 01-FEB-1995 (REL. 31, LAST ANNOTATION UPDATE) DE GAMMA-AMINOBUTYRIC-ACID RECEPTOR BETA-LIKE SUBUNIT (GABA(A) RECEPTOR). GN LCCH3. OS DROSOPHILA MELANOGASTER (FRUIT FLY). OC EUKARYOTA; METAZOA; ARTHROPODA; INSECTA; DIPTERA. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=CANTON-S; RM 93290631 RA HENDERSON J.E., SODERLUND D.M., KNIPPLE D.C.; RL BIOCHEM. BIOPHYS. RES. COMMUN. 193:474-482(1993). CC -!- SUBUNIT: GENERALLY PENTAMERIC. THERE ARE FIVE TYPES OF GABA(A) CC RECEPTOR CHAINS: ALPHA, BETA, GAMMA, DELTA, AND RHO. CC -!- SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. CC -!- SIMILARITY: BELONGS TO THE LIGAND-GATED IONIC CHANNELS FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L17436; DMGABARBS. DR EMBL; S62717; S62717. DR PIR; JN0603; JN0603. DR FLYBASE; FBGN0010240; LCCH3. KW POSTSYNAPTIC MEMBRANE; IONIC CHANNEL; GLYCOPROTEIN; SIGNAL; KW TRANSMEMBRANE. FT SIGNAL 1 27 POTENTIAL. FT CHAIN 28 496 GAMMA-AMINOBUTYRIC-ACID RECEPTOR BETA- FT LIKE SUBUNIT. FT DOMAIN 28 255 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 256 276 POTENTIAL. FT TRANSMEM 289 306 POTENTIAL. FT TRANSMEM 318 338 POTENTIAL. FT DOMAIN 339 475 CYTOPLASMIC (POTENTIAL). FT TRANSMEM 476 496 POTENTIAL. FT CARBOHYD 39 39 POTENTIAL. FT CARBOHYD 189 189 POTENTIAL. FT DISULFID 176 190 BY SIMILARITY. SQ SEQUENCE 496 AA; 56627 MW; 1329660 CN; MTCFTRVGVS CSLFFFLLGA QLQLIRCIRK DVLAGRLENV TQTISNILQG YDIRLRPNFG GEPLHVGMDL TIASFDAISE VNMDYTITMY LNQYWRDERL AFNIFGQYFD DENDDGISDV LTLSGDFAEK IWVPDTFFAN DKNSFLHDVT ERNKLVRLGG DGAVTYGMRF TTTLACMMDL HYYPLDSQNC TVEIESYGYT VSDVVMYWKP TPVRGVEDAE LPQFTIIGYE TNDRKERLAT GVYQRLSLSF KLQRNIGYFV FQTYLPSILI VMLSWVSFWI NHEATSARVA LGITTVLTMT TISTGVRSSL PRISYVKAID IYLVMCFVFV FAALLEYAAV NYTYWGKRAK KKIKKVKECC PGKIGKSERS ETCSTTEDII ELQDVRMSPI PSLRRGTYNA TLDSIGTETM NLGKFPPSFR ITRNYGTGHS QLRRRAQRGI STRPRMLHAL KRGASAIKAT IPKIKDVNII DKYSRMIFPI SFLAFNLGYW LFYILE //