ID MED7_YEAST STANDARD; PRT; 222 AA. AC Q08278; DT 28-FEB-2003 (Rel. 41, Created) DT 28-FEB-2003 (Rel. 41, Last sequence update) DT 05-JUL-2004 (Rel. 44, Last annotation update) DE RNA polymerase II mediator complex protein MED7 (RNA polymerase II DE transcriptional regulation mediator 7). GN Name=MED7; OrderedLocusNames=YOL135C; OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=S288c / FY1679; RX MEDLINE=97051593; PubMed=8896270; RX DOI=10.1002/(SICI)1097-0061(199609)12:10B<1053::AID-YEA993>3.3.CO;2-J; RA Aldea M., Piedrafita L., Casas C., Casamayor A., Khalid H., RA Balcells L., Arino J., Herrero E.; RT "Sequence analysis of a 12 801 bp fragment of the left arm of yeast RT chromosome XV containing a putative 6-phosphofructo-2-kinase gene, a RT gene for a possible glycophospholipid-anchored surface protein and six RT other open reading frames."; RL Yeast 12:1053-1058(1996). CC -!- FUNCTION: Component of the RNA polymerase II holoenzyme and the CC mediator of activation subcomplex. CC -!- SUBCELLULAR LOCATION: Nuclear (Probable). CC -!- SIMILARITY: Belongs to the MED7 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X95465; CAA64734.1; -. DR EMBL; Z74877; CAA99156.1; -. DR PIR; S66832; S66832. DR IntAct; Q08278; -. DR GermOnline; 143557; -. DR SGD; S0005495; MED7. DR GO; GO:0000119; C:mediator complex; IDA. DR GO; GO:0016455; F:RNA polymerase II transcription mediator ac...; IDA. DR GO; GO:0006366; P:transcription from Pol II promoter; IDA. DR InterPro; IPR009244; MED7. DR Pfam; PF05983; MED7; 1. KW Nuclear protein; Transcription regulation. SQ SEQUENCE 222 AA; 25585 MW; A88301E4EF3223C9 CRC64; MSNDPGNEVS SLYPPPPPYV KFFTQSNLEK LPKYKEKKAA SAKQTAPNNS NGGSEEEITC ALDYLIPPPM PKNQQYRAFG SIWQVKDQLP DLESMGLTQL YKKSTENEST NYQYKIQELR KLLKSLLLNY LELIGVLSIN PDMYERKVEN IRTILVNIHH LLNEYRPHQS RESLIMLLEE QLEYKRGEIR EIEQVCKQVH DKLTSIQDTL RTGSQSPPSS SQ //