ID 1R20_HUMAN STANDARD; PRT; 196 AA. AC Q08116; DT 01-FEB-1995 (REL. 31, CREATED) DT 01-FEB-1995 (REL. 31, LAST SEQUENCE UPDATE) DT 01-FEB-1996 (REL. 33, LAST ANNOTATION UPDATE) DE EARLY RESPONSE PROTEIN 1R20. GN 1R20. OS HOMO SAPIENS (HUMAN). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA; OC EUTHERIA; PRIMATES. RN [1] RP SEQUENCE FROM N.A. RC TISSUE=B CELL; RX MEDLINE; 94060109. RA NEWTON J.S., DEED R.W., MITCHELL E.L.D., MURPHY J.J., NORTON J.D.; RL BIOCHIM. BIOPHYS. ACTA 1216:314-316(1993). CC -!- TISSUE SPECIFICITY: B-CELL SPECIFIC. EXPRESSION IS RELATIVELY LOW CC IN B CELLS AND CHRONIC LYMPHOCYTIC LEUKAEMIA B CELLS; HOWEVER, IN CC OTHER TYPES OF MALIGNANT B CELL SUCH AS NON-HODGKIN'S LYMPHOMA AND CC HAIRY CELL LEUKAEMIA, EXPRESSION IS CONSTITUTIVELY HIGH. CC -!- INDUCTION: IN RESPONSE TO SEVERAL B-CELL ACTIVATION SIGNALS. CC -!- PTM: COULD BE PHOSPHORYLATED. CC -!- SIMILARITY: TO G0/G1 SWITCH REGULATORY PROTEIN 8. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X73427; G313215; -. DR PIR; S34157; S34157. DR PIR; S43436; S43436. DR MIM; 600323; 11TH EDITION. SQ SEQUENCE 196 AA; 22497 MW; 45C1C9FE CRC32; MPGMFFSANP KELKGTTHSL LDDKMQKRRP KTFGMDMKAY LRSMIPHLES GMKSSKSKDV LSAAEVMQWS QSLEKLLANQ TGQNVFGSFL KSEFSEENIE FWLACEDYKK TESDLLPCKA EEIYKAFVHS DAAKQINIDF RTRESTAKKI KAPTPTCFDE AQKVIYTLME KDSYPRFLKS HIYLNLLNDL QANSLK //