ID ACDS_MEGEL STANDARD; PRT; 383 AA. AC Q06319; DT 01-OCT-1996 (REL. 34, CREATED) DT 01-OCT-1996 (REL. 34, LAST SEQUENCE UPDATE) DT 01-NOV-1997 (REL. 35, LAST ANNOTATION UPDATE) DE ACYL-COA DEHYDROGENASE, SHORT-CHAIN SPECIFIC (EC 1.3.99.2) DE (SCAD) (BUTYRYL-COA DEHYDROGENASE) (BCAD). OS MEGASPHAERA ELSDENII. OC PROKARYOTA; GRACILICUTES; SCOTOBACTERIA; ANAEROBIC COCCI; OC VEILLONELLACEAE. RN [1] RP SEQUENCE FROM N.A., AND SEQUENCE OF 1-50. RX MEDLINE; 94002067. RA BECKER D.F., FUCHS J.A., BANFIELD D.K., FUNK W.D., RA MACGILLIVRAY R.T.A., STANKOVICH M.T.; RL BIOCHEMISTRY 32:10736-10742(1993). RN [2] RP X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS). RX MEDLINE; 95161388. RA DJORDJEVIC S., PACE C.P., STANKOVICH M.T., KIM J.J.P.; RL BIOCHEMISTRY 34:2163-2171(1995). CC -!- FUNCTION: HAS AN OPTIMUM SPECIFICITY FOR 4-CARBON LENGTH FATTY CC ACYL-COAS. CC -!- CATALYTIC ACTIVITY: BUTANOYL-COA + ETF = 2-BUTENOYL-COA + REDUCED CC ETF. CC -!- COFACTOR: FAD FLAVOPROTEIN. CC -!- SUBUNIT: HOMOTETRAMER. CC -!- SIMILARITY: BELONGS TO THE ACYL-COA DEHYDROGENASES FAMILY. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L04528; G149886; -. DR PDB; 1BUC; 20-APR-95. DR PROSITE; PS00072; ACYL_COA_DH_1; 1. DR PROSITE; PS00073; ACYL_COA_DH_2; 1. KW OXIDOREDUCTASE; FLAVOPROTEIN; FAD; FATTY ACID METABOLISM; KW 3D-STRUCTURE. FT ACT_SITE 367 367 BASE. FT MUTAGEN 367 367 E->Q: LOSS OF ACTIVITY. SQ SEQUENCE 383 AA; 41408 MW; 4A0C96FE CRC32; MDFNLTDIQQ DFLKLAHDFG EKKLAPTVTE RDHKGIYDKE LIDELLSLGI TGAYFEEKYG GSGDDGGDVL SYILAVEELA KYDAGVAITL SATVSLCANP IWQFGTEAQK EKFLVPLVEG TKLGAFGLTE PNAGTDASGQ QTIATKNDDG TYTLNGSKIF ITNGGAADIY IVFAMTDKSK GNHGITAFIL EDGTPGFTYG KKEDKMGIHT SQTMELVFQD VKVPAENMLG EEGKGFKIAM MTLDGGRIGV AAQALGIAEA ALADAVEYSK QRVQFGKPLC KFQSISFKLA DMKMQIEAAR NLVYKAACKK QEGKPFTVDA AIAKRVASDV AMRVTTEAVQ IFGGYGYSEE YPVARHMRDA KITQIYEGTN EVQLMVTGGA LLR //