ID IF31_YEAST STANDARD; PRT; 265 AA. AC Q05775; DT 30-MAY-2000 (Rel. 39, Created) DT 30-MAY-2000 (Rel. 39, Last sequence update) DT 10-MAY-2005 (Rel. 47, Last annotation update) DE Possible eukaryotic translation initiation factor 3 30 kDa subunit DE (eIF-3 30 kDa) (eIF3j). GN Name=HCR1; OrderedLocusNames=YLR192C; ORFNames=L8167.11; OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=S288c / AB972; RX MEDLINE=97313267; PubMed=9169871; RA Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., RA Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., RA Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., RA Heumann K., Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., RA Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., RA Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., RA Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., RA Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., RA Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., RA Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., RA Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., RA Hani J., Hoheisel J.D.; RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII."; RL Nature 387:87-90(1997). RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=S288c; RA Marsischky G., Rolfs A., Richardson A., Kane M., Baqui M., Taycher E., RA Hu Y., Vannberg F., Weger J., Kramer J., Moreira D., Kelley F., RA Zuo D., Raphael J., Hogle C., Jepson D., Williamson J., Camargo A., RA Gonzaga L., Vasconcelos A.T., Simpson A., Kolodner R., Harlow E., RA LaBaer J.; RT "Creation of the YFLEX clone resource: cloning of Saccharomyces RT cerevisiae ORFs in the Gateway recombinational cloning system."; RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. RN [3] RP CHARACTERIZATION. RX MEDLINE=99419035; PubMed=10488093; DOI=10.1074/jbc.274.39.27567; RA Valasek L., Hasek J., Trachsel H., Imre E.M., Ruis H.; RT "The Saccharomyces cerevisiae HCR1 gene encoding a homologue of the RT p35 subunit of human translation initiation factor 3 (eIF3) is a high RT copy suppressor of a temperature-sensitive mutation in the Rpg1p RT subunit of yeast eIF3."; RL J. Biol. Chem. 274:27567-27572(1999). CC -!- FUNCTION: Could be a subunit of eIF-3. Interacts with TIF32. CC -!- SUBUNIT: eIF-3 is composed of at least 8 different subunits. CC -!- INTERACTION: CC Q03195:RLI1; NbExp=1; IntAct=EBI-8944, EBI-35146; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U14913; AAB67433.1; -; Genomic_DNA. DR EMBL; AY557943; AAS56269.1; -; Genomic_DNA. DR PIR; S48545; S48545. DR IntAct; Q05775; -. DR GermOnline; 142254; -. DR Ensembl; YLR192C; Saccharomyces cerevisiae. DR SGD; S000004182; HCR1. DR LinkHub; Q05775; -. DR GO; GO:0005852; C:eukaryotic translation initiation factor 3 ...; IPI. DR GO; GO:0005515; F:protein binding; IPI. DR GO; GO:0019843; F:rRNA binding; IDA. DR GO; GO:0003743; F:translation initiation factor activity; IPI. DR GO; GO:0030490; P:processing of 20S pre-rRNA; IMP. DR GO; GO:0006412; P:protein biosynthesis; IPI. KW Complete proteome; Initiation factor; Protein biosynthesis. SQ SEQUENCE 265 AA; 29564 MW; BDDBC5943DD7F9BB CRC64; MSWDDEAING SMGNDDAVLM DSWDAEIGDD EPVMQSWDAE EEEKKPAPKP KKEQPKKVKK GKESSADRAL LDIDTLDEKT RKELIKKAEM ESDLNNAADL FAGLGVAEEH PRARALQKEQ EEQALKRPAF TKDTPIETHP LFNAETKREY QDLRKALTAA ITPMNKKSPL NYSSSLAIDL IRDVAKPMSI ESIRQTVATL NVLIKDKERE ERQARLARVR GGTATGGAGK KKVKGKTNLG GAFKKDQDFD LDGPDDFEFG DDDFM //