ID YM71_YEAST Reviewed; 267 AA. AC Q05016; DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot. DT 01-NOV-1997, sequence version 1. DT 16-DEC-2008, entry version 61. DE RecName: Full=Uncharacterized oxidoreductase YMR226C; DE EC=1.-.-.-; GN OrderedLocusNames=YMR226C; ORFNames=YM9959.08C; OS Saccharomyces cerevisiae (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=4932; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 204511 / S288c / AB972; RX MEDLINE=97313268; PubMed=9169872; RA Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., RA Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., RA Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., RA Rice P., Skelton J., Walsh S.V., Whitehead S., Barrell B.G.; RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome RT XIII."; RL Nature 387:90-93(1997). RN [2] RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. RX MEDLINE=22923965; PubMed=14562106; DOI=10.1038/nature02046; RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., RA Dephoure N., O'Shea E.K., Weissman J.S.; RT "Global analysis of protein expression in yeast."; RL Nature 425:737-741(2003). CC -!- INTERACTION: CC P10592:SSA2; NbExp=1; IntAct=EBI-27486, EBI-8603; CC -!- MISCELLANEOUS: Present with 3210 molecules/cell in log phase SD CC medium. CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases CC (SDR) family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z49939; CAA90197.1; -; Genomic_DNA. DR PIR; S57593; S57593. DR RefSeq; NP_013953.1; -. DR HSSP; P14061; 1FDU. DR DIP; DIP:1671N; -. DR IntAct; Q05016; 14. DR PeptideAtlas; Q05016; -. DR PRIDE; Q05016; -. DR Ensembl; YMR226C; Saccharomyces cerevisiae. DR GeneID; 855266; -. DR GenomeReviews; Z71257_GR; YMR226C. DR KEGG; sce:YMR226C; -. DR NMPDR; fig|4932.3.peg.5006; -. DR CYGD; YMR226c; -. DR SGD; S000004839; YMR226C. DR HOGENOM; Q05016; -. DR LinkHub; Q05016; -. DR NextBio; 978870; -. DR GermOnline; YMR226C; Saccharomyces cerevisiae. DR GO; GO:0005737; C:cytoplasm; IDA:SGD. DR GO; GO:0005634; C:nucleus; IDA:SGD. DR GO; GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:SGD. DR GO; GO:0016620; F:oxidoreductase activity, acting on the alde...; IDA:SGD. DR GO; GO:0005515; F:protein binding; IPI:IntAct. DR GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW. DR InterPro; IPR002198; DHase_sc/Rdtase_SDR. DR InterPro; IPR002347; Glc/ribitol_DHase. DR InterPro; IPR016040; NAD(P)-bd. DR Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1. DR PANTHER; PTHR19410; ADH_short_C2; 1. DR Pfam; PF00106; adh_short; 1. DR PRINTS; PR00081; GDHRDH. DR PRINTS; PR00080; SDRFAMILY. DR PROSITE; PS00061; ADH_SHORT; 1. PE 1: Evidence at protein level; KW Complete proteome; Oxidoreductase. FT CHAIN 1 267 Uncharacterized oxidoreductase YMR226C. FT /FTId=PRO_0000054873. FT NP_BIND 17 44 NAD or NADP (By similarity). FT ACT_SITE 168 168 Proton acceptor (By similarity). FT BINDING 155 155 Substrate (By similarity). SQ SEQUENCE 267 AA; 29158 MW; 77FCD713F724A9D7 CRC64; MSQGRKAAER LAKKTVLITG ASAGIGKATA LEYLEASNGD MKLILAARRL EKLEELKKTI DQEFPNAKVH VAQLDITQAE KIKPFIENLP QEFKDIDILV NNAGKALGSD RVGQIATEDI QDVFDTNVTA LINITQAVLP IFQAKNSGDI VNLGSIAGRD AYPTGSIYCA SKFAVGAFTD SLRKELINTK IRVILIAPGL VETEFSLVRY RGNEEQAKNV YKDTTPLMAD DVADLIVYAT SRKQNTVIAD TLIFPTNQAS PHHIFRG //