ID MOUB_ORNMO Reviewed; 171 AA. AC Q04669; DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot. DT 01-FEB-1994, sequence version 1. DT 02-DEC-2020, entry version 50. DE RecName: Full=Moubatin; DE Flags: Precursor; OS Ornithodoros moubata (Soft tick) (Argasid tick). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari; OC Parasitiformes; Ixodida; Ixodoidea; Argasidae; Ornithodoros. OX NCBI_TaxID=6938; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE. RX PubMed=8449907; RA Keller P.M., Waxman L., Arnold B.A., Schultz L.D., Condra C., RA Connolly T.M.; RT "Cloning of the cDNA and expression of moubatin, an inhibitor of platelet RT aggregation."; RL J. Biol. Chem. 268:5450-5456(1993). CC -!- FUNCTION: Specific inhibitor of collagen-induced platelet aggregation. CC At higher concentrations it may affect more than one aspect of platelet CC signal transduction including the thromboxane A2 receptor. CC -!- PTM: The N-terminus is blocked. CC -!- CAUTION: There are 10 AA differences between the cDNA deduced sequence CC and the determined protein sequence. These differences are not CC indicated in the paper. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L04129; AAA29432.1; -; mRNA. DR PIR; A46618; A46618. DR SMR; Q04669; -. DR Gene3D; 2.40.128.20; -; 1. DR InterPro; IPR012674; Calycin. PE 1: Evidence at protein level; KW Direct protein sequencing; Signal. FT SIGNAL 1..15 FT /evidence="ECO:0000255" FT CHAIN 16..171 FT /note="Moubatin" FT /id="PRO_0000021732" FT CONFLICT 54 FT /note="D -> DE (in Ref. 1; AA sequence)" FT /evidence="ECO:0000305" SQ SEQUENCE 171 AA; 18824 MW; 79EC7B7E460FA74B CRC64; MMLVLTTLIF SFSASIAYAQ SGCSVSDPLD ALKAFKDGAG TFLLQKSTDP QARDCLKGTP NGNRDGNTLP VTMTYKDDSK WVSLNWMFTL EGANIVATLE GKRKQRGELV YDVQSHDCHI TKLSSGVYQQ WQSNGSADDK DIKCCDEKFK ELTSGIDYTK PQEKGCETSA K //