ID LYAT_BACSU Reviewed; 306 AA. AC Q02115; DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot. DT 01-JUL-1993, sequence version 1. DT 15-JAN-2008, entry version 55. DE Membrane-bound protein lytR. GN Name=lytR; OrderedLocusNames=BSU35650; OS Bacillus subtilis. OC Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus. OX NCBI_TaxID=1423; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=168; RX MEDLINE=93018998; PubMed=1357079; RA Lazarevic V., Margot P., Soldo B., Karamata D.; RT "Sequencing and analysis of the Bacillus subtilis lytRABC divergon: a RT regulatory unit encompassing the structural genes of the N- RT acetylmuramoyl-L-alanine amidase and its modifier."; RL J. Gen. Microbiol. 138:1949-1961(1992). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=168; RX MEDLINE=98044033; PubMed=9384377; DOI=10.1038/36786; RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., RA Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., RA Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., RA Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., RA Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., RA Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., RA Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., RA Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., RA Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., RA Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., RA Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., RA Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., RA Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., RA Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., RA Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., RA Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., RA Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., RA Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., RA Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., RA Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., RA Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., RA Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., RA Yoshikawa H., Danchin A.; RT "The complete genome sequence of the Gram-positive bacterium Bacillus RT subtilis."; RL Nature 390:249-256(1997). RN [3] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 257-306. RC STRAIN=168; RX MEDLINE=94172311; PubMed=8126437; RA Soldo B., Lazarevic V., Margot P., Karamata D.; RT "Sequencing and analysis of the divergon comprising gtaB, the RT structural gene of UDP-glucose pyrophosphorylase of Bacillus subtilis RT 168."; RL J. Gen. Microbiol. 139:3185-3195(1993). CC -!- FUNCTION: Attenuator role for both its own and lytABC operon CC expression. CC -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass type II membrane CC protein (Potential). CC -!- SIMILARITY: Belongs to the lytR/cpsA/psr regulatory protein CC family. CC -!- CAUTION: This protein is unrelated to lytR from S.aureus, which is CC part of a two-component regulatory system that, together with CC lytS, is involved in autolysis and cell wall metabolism. The CC B.subtilis ortholog of S.aureus lytR is lytT (AC P94514). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M87645; AAA22578.1; -; Genomic_DNA. DR EMBL; Z99122; CAB15582.1; -; Genomic_DNA. DR EMBL; Z22516; CAA80239.1; -; Genomic_DNA. DR PIR; A47679; A47679. DR RefSeq; NP_391445.1; -. DR GeneID; 936787; -. DR GenomeReviews; AL009126_GR; BSU35650. DR KEGG; bsu:BG10404; -. DR SubtiList; BG10404; lytR. DR BioCyc; BSUB224308:BSU3562-MONOMER; -. DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. DR GO; GO:0050789; P:regulation of biological process; IEA:HAMAP. DR HAMAP; MF_01140; -; 1. DR InterPro; IPR004474; LytR_cpsA_psr. DR Pfam; PF03816; LytR_cpsA_psr; 1. DR TIGRFAMs; TIGR00350; lytR_cpsA_psr; 1. PE 3: Inferred from homology; KW Complete proteome; Membrane; Signal-anchor; Transmembrane. FT CHAIN 1 306 Membrane-bound protein lytR. FT /FTId=PRO_0000218498. FT TOPO_DOM 1 11 Cytoplasmic (Potential). FT TRANSMEM 12 32 Signal-anchor for type II membrane FT protein. FT TOPO_DOM 33 306 Extracellular (Potential). SQ SEQUENCE 306 AA; 34586 MW; E79BE5DDFFA3B089 CRC64; MRNERRKKKK TLLLTILTII GLLVLGTGGY AYYLWHKAAS TVASIHESID KSKKRDKEVS INKKDPFSVL IMGVDERDGD KGRADTLIYM TVNPKTNTTD MVSIPRDTYT KIIGKGTMDK INHSYAFGGT QMTVDTVENF LDVPVDYFVK VNMESFRDVV DTLGGITVNS TFAFSYDGYS FGKGEITLNG KEALAYTRMR KEDPRGDFGR QDRQRQVIQG IINKGANISS ITKFGDMFKV VENNVKTNLT FDNMWDIQSD YKGARKHIKQ HELKGTGTKI NGIYYYQADE SALSDITKEL KESLEK //