ID   LYAT_BACSU     STANDARD;      PRT;   306 AA.
AC   Q02115;
DT   01-JUL-1993 (Rel. 26, Created)
DT   01-JUL-1993 (Rel. 26, Last sequence update)
DT   05-JUL-2004 (Rel. 44, Last annotation update)
DE   Membrane-bound protein lytR.
GN   Name=lytR; OrderedLocusNames=BSU35650;
OS   Bacillus subtilis.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1423;
RN   [1]
RP   SEQUENCE FROM N.A.
RC   STRAIN=168;
RX   MEDLINE=93018998; PubMed=1357079;
RA   Lazarevic V., Margot P., Soldo B., Karamata D.;
RT   "Sequencing and analysis of the Bacillus subtilis lytRABC divergon: a
RT   regulatory unit encompassing the structural genes of the N-
RT   acetylmuramoyl-L-alanine amidase and its modifier.";
RL   J. Gen. Microbiol. 138:1949-1961(1992).
RN   [2]
RP   SEQUENCE FROM N.A.
RC   STRAIN=168;
RX   MEDLINE=98044033; PubMed=9384377;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G.,
RA   Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S.,
RA   Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S.,
RA   Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M.,
RA   Choi S.K., Codani J.J., Connerton I.F., Cummings N.J., Daniel R.A.,
RA   Denizot F., Devine K.M., Dusterhoft A., Ehrlich S.D., Emmerson P.T.,
RA   Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D.,
RA   Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N.,
RA   Ghim S.Y., Glaser P., Goffeau A., Golightly E.J., Grandi G.,
RA   Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A.,
RA   Hilbert H., Holsappel S., Hosono S., Hullo M.F., Itaya M., Jones L.,
RA   Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C.,
RA   Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M.,
RA   Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V.,
RA   Lee S.M., Levine A., Liu H., Masuda S., Mauel C., Medigue C.,
RA   Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M.,
RA   Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.H.,
RA   Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M.,
RA   Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S.,
RA   Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F.,
RA   Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.S., Soldo B.,
RA   Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K.,
RA   Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A.,
RA   Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A.,
RA   Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T.,
RA   Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K.,
RA   Yoshida K., Yoshikawa H.F., Zumstein E., Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   SEQUENCE OF 257-306 FROM N.A.
RC   STRAIN=168;
RX   MEDLINE=94172311; PubMed=8126437;
RA   Soldo B., Lazarevic V., Margot P., Karamata D.;
RT   "Sequencing and analysis of the divergon comprising gtaB, the
RT   structural gene of UDP-glucose pyrophosphorylase of Bacillus subtilis
RT   168.";
RL   J. Gen. Microbiol. 139:3185-3195(1993).
CC   -!- FUNCTION: Attenuator role for both its own and lytABC operon
CC       expression.
CC   -!- SUBCELLULAR LOCATION: Type II membrane protein (Potential).
CC   -!- SIMILARITY: Belongs to the lytR/cpsA/psr family of regulatory
CC       proteins.
CC   -!- CAUTION: This protein is unrelated to lytR from S.aureus, which is
CC       part of a two-component regulatory system that, together with
CC       lytS, is involved in autolysis and cell wall metabolism. The
CC       B.subtilis ortholog of S.aureus lytR is lytT (AC P94514).
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DR   EMBL; M87645; AAA22578.1; -.
DR   EMBL; Z99122; CAB15582.1; -.
DR   EMBL; Z22516; CAA80239.1; -.
DR   PIR; A47679; A47679.
DR   SubtiList; BG10404; lytR.
DR   HAMAP; MF_01140; -; 1.
DR   InterPro; IPR004474; LytR_cpsA_psr.
DR   Pfam; PF03816; LytR_cpsA_psr; 1.
DR   TIGRFAMs; TIGR00350; lytR_cpsA_psr; 1.
KW   Transmembrane; Signal-anchor; Complete proteome.
FT   DOMAIN        1     11       Cytoplasmic (Potential).
FT   TRANSMEM     12     32       Signal-anchor for type II membrane
FT                                protein.
FT   DOMAIN       33    306       Extracellular (Potential).
SQ   SEQUENCE   306 AA;  34586 MW;  E79BE5DDFFA3B089 CRC64;
     MRNERRKKKK TLLLTILTII GLLVLGTGGY AYYLWHKAAS TVASIHESID KSKKRDKEVS
     INKKDPFSVL IMGVDERDGD KGRADTLIYM TVNPKTNTTD MVSIPRDTYT KIIGKGTMDK
     INHSYAFGGT QMTVDTVENF LDVPVDYFVK VNMESFRDVV DTLGGITVNS TFAFSYDGYS
     FGKGEITLNG KEALAYTRMR KEDPRGDFGR QDRQRQVIQG IINKGANISS ITKFGDMFKV
     VENNVKTNLT FDNMWDIQSD YKGARKHIKQ HELKGTGTKI NGIYYYQADE SALSDITKEL
     KESLEK
//