ID KRUP_TRICA Reviewed; 74 AA. AC Q01793; DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot. DT 01-JUL-1993, sequence version 1. DT 06-MAR-2013, entry version 72. DE RecName: Full=Protein krueppel; DE Flags: Fragment; GN Name=Kr; OS Tribolium castaneum (Red flour beetle). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; OC Cucujiformia; Tenebrionidae; Tribolium. OX NCBI_TaxID=7070; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX MEDLINE=93066327; PubMed=1438276; DOI=10.1073/pnas.89.22.10782; RA Sommer R.J., Retzlaff M., Goerlich K., Sander K., Tautz D.; RT "Evolutionary conservation pattern of zinc-finger domains of RT Drosophila segmentation genes."; RL Proc. Natl. Acad. Sci. U.S.A. 89:10782-10786(1992). CC -!- FUNCTION: Krueppel is a gap class segmentation protein. CC -!- SUBCELLULAR LOCATION: Nucleus (Probable). CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein CC family. CC -!- SIMILARITY: Contains 4 C2H2-type zinc fingers. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L01616; AAA30096.1; -; Genomic_DNA. DR UniGene; Tca.5796; -. DR ProteinModelPortal; Q01793; -. DR eggNOG; COG5048; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0035282; P:segmentation; IEA:UniProtKB-KW. DR Gene3D; 3.30.160.60; -; 2. DR InterPro; IPR007087; Znf_C2H2. DR InterPro; IPR015880; Znf_C2H2-like. DR InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd. DR SMART; SM00355; ZnF_C2H2; 2. DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2. DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2. PE 3: Inferred from homology; KW Developmental protein; DNA-binding; Gap protein; Metal-binding; KW Nucleus; Repeat; Zinc; Zinc-finger. FT CHAIN <1 >74 Protein krueppel. FT /FTId=PRO_0000047002. FT ZN_FING <1 4 C2H2-type 1. FT ZN_FING 10 32 C2H2-type 2. FT ZN_FING 38 60 C2H2-type 3. FT ZN_FING 66 >74 C2H2-type 4. FT NON_TER 1 1 FT NON_TER 74 74 SQ SEQUENCE 74 AA; 9065 MW; 902C9B81C8D469DA CRC64; ERTHTGEKPF ECQECHKRFT RDHHLKTHMR LHTGERPYRC EHCDRQFVQV ANLRRHLRVH TGERPYGCEH CSMK //