ID HRPN_ERWAM Reviewed; 403 AA. AC Q01099; DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot. DT 30-MAY-2000, sequence version 3. DT 03-MAY-2023, entry version 64. DE RecName: Full=Harpin HrpN; DE AltName: Full=Harpin-Ea; GN Name=hrpN; OS Erwinia amylovora (Fire blight bacteria). OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; OC Erwiniaceae; Erwinia. OX NCBI_TaxID=552; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-15. RC STRAIN=Ea321; RX PubMed=1621099; DOI=10.1126/science.1621099; RA Wei Z.-M., Laby R.J., Zumoff C.H., Bauer D.W., He S.Y., Collmer A., RA Beer S.V.; RT "Harpin, elicitor of the hypersensitive response produced by the plant RT pathogen Erwinia amylovora."; RL Science 257:85-88(1992). RN [2] RP SEQUENCE REVISION. RA Laby R.J., Kim J.F., Beer S.V.; RL Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Elicits the hypersensitive response (HR) in the plant upon CC infection. Harpin elicits HR in non-hosts and is also required for CC pathogenicity in host plants. CC -!- SUBCELLULAR LOCATION: Secreted. Note=Via the HRP secretion pathway. CC -!- SIMILARITY: Belongs to the harpin HrpN family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M92994; AAC31644.2; -; Genomic_DNA. DR PIR; T08471; T08471. DR RefSeq; WP_004155369.1; NZ_RQKG01000002.1. DR AlphaFoldDB; Q01099; -. DR GeneID; 8913118; -. DR PATRIC; fig|665029.3.peg.571; -. DR PHI-base; PHI:2467; -. DR PHI-base; PHI:2475; -. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW. DR InterPro; IPR006961; HrpN/Z. DR Pfam; PF04877; Harpin; 1. PE 1: Evidence at protein level; KW Direct protein sequencing; Hypersensitive response elicitation; Secreted. FT CHAIN 1..403 FT /note="Harpin HrpN" FT /id="PRO_0000084067" FT REGION 113..157 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 173..195 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 173..192 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 403 AA; 39697 MW; 146FA642351D8E87 CRC64; MSLNTSGLGA STMQISIGGA GGNNGLLGTS RQNAGLGGNS ALGLGGGNQN DTVNQLAGLL TGMMMMMSMM GGGGLMGGGL GGGLGNGLGG SGGLGEGLSN ALNDMLGGSL NTLGSKGGNN TTSTTNSPLD QALGINSTSQ NDDSTSGTDS TSDSSDPMQQ LLKMFSEIMQ SLFGDGQDGT QGSSSGGKQP TEGEQNAYKK GVTDALSGLM GNGLSQLLGN GGLGGGQGGN AGTGLDGSSL GGKGLQNLSG PVDYQQLGNA VGTGIGMKAG IQALNDIGTH SDSSTRSFVN KGDRAMAKEI GQFMDQYPEV FGKPQYQKGP GQEVKTDDKS WAKALSKPDD DGMTPASMEQ FNKAKGMIKS AMAGDTGNGN LQARGAGGSS LGIDAMMAGD AINNMALGKL GAA //