ID Q00GN8_LEPAN Unreviewed; 459 AA. AC Q00GN8; DT 14-NOV-2006, integrated into UniProtKB/TrEMBL. DT 14-NOV-2006, sequence version 1. DT 08-APR-2008, entry version 11. DE NADH-ubiquinone oxidoreductase chain 4 (EC 1.6.5.3). OS Lepilemur ankaranensis (Ankarana sportive lemur). OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; OC Lemuriformes; Lepilemuridae; Lepilemur. OX NCBI_TaxID=342401; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=LABE5.17, LABE5.4, LABE5.3, LABE5.2, LABE5.1, FIA5.13, FIA5.12, RC FIA5.11, FIA5.9, FIA5.6, FIA5.5, FIA5.1, LAME5.8, and LAME5.6; RA Louis E.E. Jr, Engberg S.E., Lei R., Geng H., Sommer J.A., RA Randriamampionona R., Randriamanana J.C., Zaonarivelo J.R., RA Andriantompohavana R., Randria G., Prosper, Ramaromilanto B., RA Rakotoarisoa G., Rooney A., Brenneman R.A.; RT "Molecular and morphological analyses of the sportive lemurs (Family RT Megaladapidae: Genus Lepilemur) reveals 11 previously unrecognized RT species."; RL Spec. Publ. Mus. Tex. Tech. Univ. 49:1-47(2006). CC -!- CATALYTIC ACTIVITY: NADH + ubiquinone = NAD(+) + ubiquinol. CC -!- SIMILARITY: Belongs to the complex I subunit 4 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; DQ529712; ABG74167.1; -; Genomic_DNA. DR EMBL; DQ529713; ABG74171.1; -; Genomic_DNA. DR EMBL; DQ529714; ABG74175.1; -; Genomic_DNA. DR EMBL; DQ529715; ABG74179.1; -; Genomic_DNA. DR EMBL; DQ529716; ABG74183.1; -; Genomic_DNA. DR EMBL; DQ529719; ABG74195.1; -; Genomic_DNA. DR EMBL; DQ529721; ABG74203.1; -; Genomic_DNA. DR EMBL; DQ529722; ABG74207.1; -; Genomic_DNA. DR EMBL; DQ529723; ABG74211.1; -; Genomic_DNA. DR EMBL; DQ529739; ABG74275.1; -; Genomic_DNA. DR EMBL; DQ529740; ABG74279.1; -; Genomic_DNA. DR EMBL; DQ529741; ABG74283.1; -; Genomic_DNA. DR EMBL; DQ529742; ABG74287.1; -; Genomic_DNA. DR EMBL; DQ529743; ABG74291.1; -; Genomic_DNA. DR GO; GO:0005739; C:mitochondrion; IEA:InterPro. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro. DR GO; GO:0006120; P:mitochondrial electron transport, NADH to u...; IEA:InterPro. DR InterPro; IPR010227; NADH_quinone_OxRdtase_I_M. DR InterPro; IPR003918; NADHub_OxRdtase_4. DR InterPro; IPR001750; Oxidored_q1. DR InterPro; IPR000260; OxRdtase_q5_N. DR Pfam; PF00361; Oxidored_q1; 1. DR Pfam; PF01059; Oxidored_q5_N; 1. DR PRINTS; PR01437; NUOXDRDTASE4. DR TIGRFAMs; TIGR01972; NDH_I_M; 1. PE 3: Inferred from homology; KW Electron transport; Mitochondrion; NAD; Oxidoreductase; KW Respiratory chain; Transport; Ubiquinone. SQ SEQUENCE 459 AA; 52177 MW; 3BEAEAD636206142 CRC64; MLKIIIPTIM LLPVTWFSAN SMVWINITLH SLTISLMSLS FLNQTDSNSN NFSSTFFSDP LSSPLLTLTM WLLPLTIMAS QHHLSKEPWE RKKYFLFTLI SLQLFLIMTF TATELIMFYI LFESTLIPTL IIITRWGNQT ERLNAGLYFL FYTLIGSLPL LVALSFIQKH MGTLNLFMMT YWSQELPNSW SSNLMWMACI MAFMIKMPLY GLHLWLPKAH VEAPIAGSMI LAAILLKLGG YGMMRITTIL NPLTKFMAYP FLMLCLWGMI MTSLICLRQT DLKSLIAYSS VSHMALVIVA ILIQTPWSFM GATALMIAHG LTSSMLFCLA NSNYERIHNR TMLLARGLQS LLPLMSTWWL LASLTNLALP PSINLIGELF ITMATFSWSN MTIILTGLNM LITATYSLHM LAMTQRGKSL YHMHNLNPSL TRENTLMSMH IFPLLLLTLN PNILMGPTY //