ID ESXI_MYCTU Reviewed; 94 AA. AC P9WNK1; L0TEQ6; O08120; O08122; P96364; Q9L781; DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot. DT 16-APR-2014, sequence version 1. DT 27-MAY-2015, entry version 11. DE RecName: Full=ESAT-6-like protein EsxI; DE AltName: Full=Antigen Mtb9.9B; GN OrderedLocusNames=Rv1037c; ORFNames=MTCY10G2.12; GN and GN OrderedLocusNames=Rv3619c; ORFNames=MTCY07H7B.03, MTCY15C10.33; OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Corynebacterineae; Mycobacteriaceae; Mycobacterium; OC Mycobacterium tuberculosis complex. OX NCBI_TaxID=83332; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 35801 / TMC 107 / Erdman; RX PubMed=10662800; DOI=10.1084/jem.191.3.551; RA Alderson M.R., Bement T., Day C.H., Zhu L., Molesh D., Skeiky Y.A.W., RA Coler R., Lewinsohn D.M., Reed S.G., Dillon D.C.; RT "Expression cloning of an immunodominant family of Mycobacterium RT tuberculosis antigens using human CD4(+) T cells."; RL J. Exp. Med. 191:551-560(2000). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 25618 / H37Rv; RX PubMed=9634230; DOI=10.1038/31159; RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., RA Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, RA Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., RA Connor R., Davies R.M., Devlin K., Feltwell T., Gentles S., Hamlin N., RA Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., RA Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., RA Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., RA Sulston J.E., Taylor K., Whitehead S., Barrell B.G.; RT "Deciphering the biology of Mycobacterium tuberculosis from the RT complete genome sequence."; RL Nature 393:537-544(1998). CC -!- INTERACTION: CC P9WNI3:Rv3620c; NbExp=2; IntAct=EBI-8531756, EBI-8531788; CC -!- SIMILARITY: Belongs to the ESAT-6 (esx) family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF226277; AAF32406.1; -; Genomic_DNA. DR EMBL; AL123456; CCP43788.1; -; Genomic_DNA. DR EMBL; AL123456; CCP46442.1; -; Genomic_DNA. DR PIR; D70560; D70560. DR RefSeq; NP_215553.1; NC_000962.3. DR RefSeq; NP_218136.1; NC_000962.3. DR RefSeq; WP_003898699.1; NZ_KK339374.1. DR RefSeq; YP_006514400.1; NC_018143.2. DR RefSeq; YP_006517108.1; NC_018143.2. DR ProteinModelPortal; P9WNK1; -. DR SMR; P9WNK1; 9-69. DR IntAct; P9WNK1; 1. DR EnsemblBacteria; CCP43788; CCP43788; Rv1037c. DR EnsemblBacteria; CCP46442; CCP46442; Rv3619c. DR GeneID; 885328; -. DR GeneID; 888299; -. DR KEGG; mtu:Rv1037c; -. DR KEGG; mtu:Rv3619c; -. DR KEGG; mtv:RVBD_1037c; -. DR KEGG; mtv:RVBD_3619c; -. DR TubercuList; Rv1037c; -. DR TubercuList; Rv3619c; -. DR PhylomeDB; P9WNK1; -. DR Proteomes; UP000001584; Chromosome. DR GO; GO:0005618; C:cell wall; IDA:MTBBASE. DR InterPro; IPR009416; DUF1066. DR InterPro; IPR010310; T7SS_ESAT-6-like. DR Pfam; PF06013; WXG100; 1. DR PIRSF; PIRSF037656; DUF1066; 1. DR SUPFAM; SSF140453; SSF140453; 1. PE 1: Evidence at protein level; KW Complete proteome; Reference proteome. FT CHAIN 1 94 ESAT-6-like protein EsxI. FT /FTId=PRO_0000167800. FT CONFLICT 20 20 Q -> L (in Ref. 1; AAF32406). FT {ECO:0000305}. FT CONFLICT 23 23 S -> L (in Ref. 1; AAF32406). FT {ECO:0000305}. SQ SEQUENCE 94 AA; 9833 MW; 8F971BB03789C57E CRC64; MTINYQFGDV DAHGAMIRAQ AGSLEAEHQA IISDVLTASD FWGGAGSAAC QGFITQLGRN FQVIYEQANA HGQKVQAAGN NMAQTDSAVG SSWA //