ID HPPD_ARATH STANDARD; PRT; 445 AA. AC P93836; O04330; DT 15-JUL-1998 (Rel. 36, Created) DT 15-JUL-1998 (Rel. 36, Last sequence update) DT 15-DEC-1998 (Rel. 37, Last annotation update) DE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (EC 1.13.11.27) (4HPPD) (HPD). GN HPD. OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Embryophyta; Tracheophyta; Spermatophyta; OC Magnoliophyta; eudicotyledons; Rosidae; eurosids II; Brassicales; OC Brassicaceae; Arabidopsis. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=CV. WASSILEWSKIJA; RA Bartley G.E., Maxwell C.A., Wittenbach V.A., Scolnik P.A.; RT "Cloning of an Arabidopsis thaliana cDNA for p-hydroxyphenylpyruvate RT dioxygenase."; RL (In) Plant Gene Register PGR97-065. RN [2] RP SEQUENCE FROM N.A. RC STRAIN=CV. COLUMBIA; RA Norris S.R., Dellapenna D.; RL Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases. RN [3] RP SEQUENCE FROM N.A. RC STRAIN=CV. COLUMBIA; RA Hsieh T.-F., Rodgers M., Matringe M.; RL Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: 4-HYDROXYPHENYLPYRUVATE + O(2) = CC HOMOGENTISATE + CO(2). CC -!- COFACTOR: IRON (BY SIMILARITY). CC -!- PATHWAY: PARTICIPATES IN THE CATABOLISM OF TYROSINE. IN THE CC PATHWAY FOR BIOSYNTHESIS OF PRENYLQUINONES. CC -!- SUBCELLULAR LOCATION: CYTOPLASMIC (BY SIMILARITY). CC -!- SIMILARITY: BELONGS TO THE 4HPPD FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U89267; AAB70025.1; -. DR EMBL; AF000228; AAB58404.1; -. DR EMBL; AF047834; AAC15697.1; -. DR INTERPRO; IPR002887; -. DR PFAM; PF01626; 4HPPD_C; 1. KW Oxidoreductase; Dioxygenase; Iron. SQ SEQUENCE 445 AA; 48816 MW; FD0442F93556B3F5 CRC64; MGHQNAAVSE NQNHDDGAAS SPGFKLVGFS KFVRKNPKSD KFKVKRFHHI EFWCGDATNV ARRFSWGLGM RFSAKSDLST GNMVHASYLL TSGDLRFLFT APYSPSLSAG EIKPTTTASI PSFDHGSCRS FFSSHGLGVR AVAIEVEDAE SAFSISVANG AIPSSPPIVL NEAVTIAEVK LYGDVVLRYV SYKAEDTEKS EFLPGFERVE DASSFPLDYG IRRLDHAVGN VPELGPALTY VAGFTGFHQF AEFTADDVGT AESGLNSAVL ASNDEMVLLP INEPVHGTKR KSQIQTYLEH NEGAGLQHLA LMSEDIFRTL REMRKRSSIG GFDFMPSPPP TYYQNLKKRV GDVLSDDQIK ECEELGILVD RDDQGTLLQI FTKPLGDRPT IFIEIIQRVG CMMKDEEGKA YQSGGCGGFG KGNFSELFKS IEEYEKTLEA KQLVG //