ID SODC1_MESCR Reviewed; 152 AA. AC P93258; DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-1997, sequence version 1. DT 18-SEP-2013, entry version 75. DE RecName: Full=Superoxide dismutase [Cu-Zn] 1; DE EC=1.15.1.1; GN Name=SODCC.1; Synonyms=SOD, SOD1; OS Mesembryanthemum crystallinum (Common ice plant) (Cryophytum OS crystallinum). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; OC Caryophyllales; Aizoaceae; Mesembryanthemum. OX NCBI_TaxID=3544; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RA Michalowski C.B., Quigley-Landreau F., Bohnert H.J.; RL Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Destroys radicals which are normally produced within the CC cells and which are toxic to biological systems. CC -!- CATALYTIC ACTIVITY: 2 superoxide + 2 H(+) = O(2) + H(2)O(2). CC -!- COFACTOR: Binds 1 copper ion per subunit (By similarity). CC -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity). CC -!- SUBUNIT: Homodimer (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm. CC -!- SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U80069; AAB40394.1; -; mRNA. DR ProteinModelPortal; P93258; -. DR SMR; P93258; 1-152. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0004784; F:superoxide dismutase activity; IEA:EC. DR GO; GO:0006801; P:superoxide metabolic process; IEA:InterPro. DR Gene3D; 2.60.40.200; -; 1. DR InterPro; IPR024134; SOD_Cu/Zn_/chaperone. DR InterPro; IPR018152; SOD_Cu/Zn_BS. DR InterPro; IPR001424; SOD_Cu_Zn_dom. DR PANTHER; PTHR10003; PTHR10003; 1. DR Pfam; PF00080; Sod_Cu; 1. DR PRINTS; PR00068; CUZNDISMTASE. DR SUPFAM; SSF49329; SOD_Cu_Zn; 1. DR PROSITE; PS00087; SOD_CU_ZN_1; 1. DR PROSITE; PS00332; SOD_CU_ZN_2; 1. PE 2: Evidence at transcript level; KW Antioxidant; Copper; Cytoplasm; Disulfide bond; Metal-binding; KW Oxidoreductase; Zinc. FT CHAIN 1 152 Superoxide dismutase [Cu-Zn] 1. FT /FTId=PRO_0000164144. FT METAL 45 45 Copper; catalytic (By similarity). FT METAL 47 47 Copper; catalytic (By similarity). FT METAL 62 62 Copper; catalytic (By similarity). FT METAL 62 62 Zinc; structural (By similarity). FT METAL 70 70 Zinc; structural (By similarity). FT METAL 79 79 Zinc; structural (By similarity). FT METAL 82 82 Zinc; structural (By similarity). FT METAL 119 119 Copper; catalytic (By similarity). FT DISULFID 56 145 By similarity. SQ SEQUENCE 152 AA; 15173 MW; 44771D3714ADB19C CRC64; MVKAVVVLSS SEGVSGTVQF TQEGSGPTTV TGNVSGLRPG LHGFHVHALG DTTNGCMSTG PHFNPAGKEH GAPEDETRHA GDLGNITVGD DGTATFTIID SQIPLTGPNS IVGRAVVVHA DPDDLGRGGH ELSKATGNAG GRVACGVIGL QG //