ID SODC1_MESCR Reviewed; 152 AA. AC P93258; DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-1997, sequence version 1. DT 28-NOV-2006, entry version 46. DE Superoxide dismutase [Cu-Zn] 1 (EC 1.15.1.1). GN Name=SODCC.1; Synonyms=SOD, SOD1; OS Mesembryanthemum crystallinum (Common ice plant). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; OC Caryophyllales; Aizoaceae; Mesembryanthemum. OX NCBI_TaxID=3544; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RA Michalowski C.B., Quigley-Landreau F., Bohnert H.J.; RL Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Destroys radicals which are normally produced within the CC cells and which are toxic to biological systems. CC -!- CATALYTIC ACTIVITY: 2 superoxide + 2 H(+) = O(2) + H(2)O(2). CC -!- COFACTOR: Binds 1 copper ion per subunit (By similarity). CC -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity). CC -!- SUBUNIT: Homodimer (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm. CC -!- SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U80069; AAB40394.1; -; mRNA. DR HSSP; P00441; 1OZU. DR SMR; P93258; 3-150. DR InterPro; IPR001424; SOD_Cu_Zn. DR Gene3D; G3DSA:2.60.40.200; SOD_Cu_Zn; 1. DR Pfam; PF00080; Sod_Cu; 1. DR PRINTS; PR00068; CUZNDISMTASE. DR ProDom; PD000469; SOD_CU_ZN; 1. DR PROSITE; PS00087; SOD_CU_ZN_1; 1. DR PROSITE; PS00332; SOD_CU_ZN_2; 1. KW Antioxidant; Copper; Metal-binding; Oxidoreductase; Zinc. FT CHAIN 1 152 Superoxide dismutase [Cu-Zn] 1. FT /FTId=PRO_0000164144. FT METAL 45 45 Copper (catalytic) (By similarity). FT METAL 47 47 Copper (catalytic) (By similarity). FT METAL 62 62 Copper (catalytic) (By similarity). FT METAL 62 62 Zinc (structural) (By similarity). FT METAL 70 70 Zinc (structural) (By similarity). FT METAL 79 79 Zinc (structural) (By similarity). FT METAL 82 82 Zinc (structural) (By similarity). FT METAL 119 119 Copper (catalytic) (By similarity). FT DISULFID 56 145 By similarity. SQ SEQUENCE 152 AA; 15173 MW; 44771D3714ADB19C CRC64; MVKAVVVLSS SEGVSGTVQF TQEGSGPTTV TGNVSGLRPG LHGFHVHALG DTTNGCMSTG PHFNPAGKEH GAPEDETRHA GDLGNITVGD DGTATFTIID SQIPLTGPNS IVGRAVVVHA DPDDLGRGGH ELSKATGNAG GRVACGVIGL QG //