ID COX3_ARATH STANDARD; PRT; 265 AA. AC P92514; DT 01-NOV-1997 (Rel. 35, Created) DT 16-OCT-2001 (Rel. 40, Last sequence update) DT 10-MAY-2005 (Rel. 47, Last annotation update) DE Cytochrome c oxidase subunit 3 (EC 1.9.3.1) (Cytochrome c oxidase DE polypeptide III). GN Name=COX3; OrderedLocusNames=AtMg00730; OS Arabidopsis thaliana (Mouse-ear cress). OG Mitochondrion. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicots; rosids; OC eurosids II; Brassicales; Brassicaceae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX MEDLINE=97141919; PubMed=8988169; RA Unseld M., Marienfeld J.R., Brandt P., Brennicke A.; RT "The mitochondrial genome of Arabidopsis thaliana contains 57 genes in RT 366,924 nucleotides."; RL Nat. Genet. 15:57-61(1997). RN [2] RP RNA EDITING. RX MEDLINE=20079652; PubMed=10611383; DOI=10.1073/pnas.96.26.15324; RA Giege P., Brennicke A.; RT "RNA editing in Arabidopsis mitochondria effects 441 C to U changes in RT ORFs."; RL Proc. Natl. Acad. Sci. U.S.A. 96:15324-15329(1999). CC -!- FUNCTION: Subunits I, II and III form the functional core of the CC enzyme complex. CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) = 4 ferricytochrome CC c + 2 H(2)O. CC -!- SUBCELLULAR LOCATION: Integral membrane protein. Mitochondrial CC inner membrane. CC -!- RNA EDITING: Modified_positions=38, 82, 86, 104, 105, 138, 141. CC -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 3 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Y08502; CAA69818.3; ALT_SEQ; Genomic_DNA. DR InterPro; IPR000298; CytC_oxdse_III. DR Pfam; PF00510; COX3; 1. DR ProDom; PD000382; CytC_oxdse_III; 1. DR PROSITE; PS50253; COX3; 1. KW Mitochondrion; Oxidoreductase; RNA editing; Transmembrane. FT TRANSMEM 41 61 Potential. FT TRANSMEM 85 105 Potential. FT TRANSMEM 137 157 Potential. FT TRANSMEM 162 182 Potential. FT TRANSMEM 200 220 Potential. FT TRANSMEM 245 265 Potential. SQ SEQUENCE 265 AA; 29961 MW; 753978DE1CAA13F1 CRC64; MIESQRHSYH LVDPSPWPIS GSLGALATTV GGVMYMHSFQ GGARLLSLGL IFILYTMFVW WRDVLRESTL EGHHTKVVQL GLRYGFILFI VSEVMFFFAF FWAFFHSSLA PAVEIGGIWP PKGIEVLDPW EIPFLNTLIL LSSGAAVTWA HHAILAGKEK RAVYALVATV LLALVFTGFQ GMEYYQAPFT ISDSIYGSTF FLATGFHGFH VIIGTLFLII CGIRQYLGHL TKEHHVGFEA AAWYWHFVDV VWLFLFVSIY WWGGI //