ID VIP_MACMU Reviewed; 28 AA. AC P84488; DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot. DT 29-MAR-2005, sequence version 1. DT 08-JUN-2016, entry version 49. DE RecName: Full=Vasoactive intestinal peptide; DE Short=VIP; DE AltName: Full=Vasoactive intestinal polypeptide; GN Name=VIP; OS Macaca mulatta (Rhesus macaque). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. OX NCBI_TaxID=9544; RN [1] RP PROTEIN SEQUENCE. RX PubMed=2003150; DOI=10.1016/0167-0115(91)90005-2; RA Yu J.-H., Xin Y., Eng J., Yalow R.S.; RT "Rhesus monkey gastroenteropancreatic hormones: relationship to human RT sequences."; RL Regul. Pept. 32:39-45(1991). CC -!- FUNCTION: VIP causes vasodilation, lowers arterial blood pressure, CC stimulates myocardial contractility, increases glycogenolysis and CC relaxes the smooth muscle of trachea, stomach and gall bladder. CC -!- SUBCELLULAR LOCATION: Secreted. CC -!- SIMILARITY: Belongs to the glucagon family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR PIR; B60071; B60071. DR UniGene; Mmu.17274; -. DR STRING; 9544.ENSMMUP00000025076; -. DR eggNOG; ENOG410IW68; Eukaryota. DR eggNOG; ENOG4111JKK; LUCA. DR HOGENOM; HOG000253943; -. DR HOVERGEN; HBG008141; -. DR InParanoid; P84488; -. DR Proteomes; UP000006718; Unplaced. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR GO; GO:0048255; P:mRNA stabilization; ISS:AgBase. DR GO; GO:0070459; P:prolactin secretion; ISS:AgBase. DR InterPro; IPR000532; Glucagon_GIP_secretin_VIP. DR InterPro; IPR015523; VIP. DR PANTHER; PTHR11213:SF5; PTHR11213:SF5; 1. DR Pfam; PF00123; Hormone_2; 1. DR SMART; SM00070; GLUCA; 1. DR PROSITE; PS00260; GLUCAGON; 1. PE 1: Evidence at protein level; KW Amidation; Complete proteome; Direct protein sequencing; Hormone; KW Reference proteome; Secreted. FT PEPTIDE 1 28 Vasoactive intestinal peptide. FT /FTId=PRO_0000043942. FT MOD_RES 28 28 Asparagine amide. SQ SEQUENCE 28 AA; 3327 MW; EF313FB573FF6F3F CRC64; HSDAVFTDNY TRLRKQMAVK KYLNSILN //