ID PLS_HALLA Reviewed; 84 AA. AC P82595; DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot. DT 26-SEP-2001, sequence version 2. DT 24-JUL-2007, entry version 28. DE Perlustrin. OS Haliotis laevigata (Abalone). OC Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda; OC Vetigastropoda; Haliotoidea; Haliotidae; Haliotis. OX NCBI_TaxID=36097; RN [1] RP PROTEIN SEQUENCE, AND MASS SPECTROMETRY. RC TISSUE=Shell; RX MEDLINE=21338199; PubMed=11444832; DOI=10.1006/bbrc.2001.5170; RA Weiss I.M., Goehring W., Fritz M., Mann K.; RT "Perlustrin, a Haliotis laevigata (abalone) nacre protein, is RT homologous to the insulin-like growth factor binding protein N- RT terminal module of vertebrates."; RL Biochem. Biophys. Res. Commun. 285:244-249(2001). RN [2] RP PROTEIN SEQUENCE OF 1-33. RC TISSUE=Shell; RX MEDLINE=20090585; PubMed=10623567; DOI=10.1006/bbrc.1999.1907; RA Weiss I.M., Kaufmann S., Mann K., Fritz M.; RT "Purification and characterization of perlucin and perlustrin, two new RT proteins from the shell of the mollusc Haliotis laevigata."; RL Biochem. Biophys. Res. Commun. 267:17-21(2000). CC -!- FUNCTION: Binds human IGF-I and IGF-II and bovine insulin. CC -!- TISSUE SPECIFICITY: Shell. CC -!- MASS SPECTROMETRY: MW=9325.8; METHOD=Electrospray; RANGE=1-84; CC NOTE=Ref.1. CC -!- SIMILARITY: Contains 1 IGFBP domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR InterPro; IPR009168; IGFBP1-6. DR InterPro; IPR000867; IGFBP_like. DR PANTHER; PTHR11551; IGFBP1-6; 1. DR SMART; SM00121; IB; 1. DR PROSITE; PS00222; IGF_BINDING; 1. PE 1: Evidence at protein level; KW Direct protein sequencing; Growth factor binding. FT CHAIN 1 84 Perlustrin. FT /FTId=PRO_0000152777. SQ SEQUENCE 84 AA; 9338 MW; 42B47741B9101A5B CRC64; LSCASCENAA CPAIGLPCKP SEYVYTPCGC CPQCPLELGQ PCGSFTQRCQ FDLWCLRRKG NKIEAYKYVP WHLDFKGVCA RVDV //