ID PLS_HALLA STANDARD; PRT; 84 AA. AC P82595; DT 16-OCT-2001 (Rel. 40, Created) DT 16-OCT-2001 (Rel. 40, Last sequence update) DT 28-FEB-2003 (Rel. 41, Last annotation update) DE Perlustrin. OS Haliotis laevigata (Abalone). OC Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda; OC Vetigastropoda; Haliotoidea; Haliotidae; Haliotis. OX NCBI_TaxID=36097; RN [1] RP SEQUENCE, AND MASS SPECTROMETRY. RC TISSUE=Shell; RX MEDLINE=21338199; PubMed=11444832; RA Weiss I.M., Goehring W., Fritz M., Mann K.; RT "Perlustrin, a Haliotis laevigata (abalone) nacre protein, is RT homologous to the insulin-like growth factor binding protein RT N-terminal module of vertebrates."; RL Biochem. Biophys. Res. Commun. 285:244-249(2001). RN [2] RP SEQUENCE OF 1-33. RC TISSUE=Shell; RX MEDLINE=20090585; PubMed=10623567; RA Weiss I.M., Kaufmann S., Mann K., Fritz M.; RT "Purification and characterization of perlucin and perlustrin, two new RT proteins from the shell of the mollusc Haliotis laevigata."; RL Biochem. Biophys. Res. Commun. 267:17-21(2000). CC -!- FUNCTION: Binds human IGF-I and IGF-II and bovine insulin. CC -!- TISSUE SPECIFICITY: Shell. CC -!- MASS SPECTROMETRY: MW=9325.8; METHOD=Electrospray. CC -!- SIMILARITY: Contains 1 IGFBP domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR InterPro; IPR009030; Grow_fac_recep. DR InterPro; IPR000867; Insl_gro_fac_pr. DR SMART; SM00121; IB; 1. DR PROSITE; PS00222; IGF_BINDING; FALSE_NEG. KW Growth factor binding. SQ SEQUENCE 84 AA; 9338 MW; 42B47741B9101A5B CRC64; LSCASCENAA CPAIGLPCKP SEYVYTPCGC CPQCPLELGQ PCGSFTQRCQ FDLWCLRRKG NKIEAYKYVP WHLDFKGVCA RVDV //