ID PCW6_PACGO Reviewed; 20 AA. AC P82428; DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot. DT 26-SEP-2001, sequence version 1. DT 03-OCT-2012, entry version 45. DE RecName: Full=Ponericin-W6; OS Pachycondyla goeldii (Ponerine ant). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; OC Vespoidea; Formicidae; Ponerinae; Ponerini; Pachycondyla. OX NCBI_TaxID=118888; RN [1] RP PROTEIN SEQUENCE, FUNCTION, MASS SPECTROMETRY, AND AMIDATION. RC TISSUE=Venom; RX MEDLINE=21264562; PubMed=11279030; DOI=10.1074/jbc.M100216200; RA Orivel J., Redeker V., Le Caer J.-P., Krier F., Revol-Junelles A.-M., RA Longeon A., Chafotte A., Dejean A., Rossier J.; RT "Ponericins, new antibacterial and insecticidal peptides from the RT venom of the ant Pachycondyla goeldii."; RL J. Biol. Chem. 276:17823-17829(2001). CC -!- FUNCTION: Activity against Gram-positive bacteria. Has CC insecticidal and hemolytic activities. CC -!- SUBCELLULAR LOCATION: Secreted. CC -!- TISSUE SPECIFICITY: Expressed by the venom gland. CC -!- MASS SPECTROMETRY: Mass=2029.40; Method=MALDI; Range=1-20; CC Source=PubMed:11279030; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. DR GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW. DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW. DR GO; GO:0044179; P:hemolysis in other organism; IEA:UniProtKB-KW. PE 1: Evidence at protein level; KW Amidation; Antibiotic; Antimicrobial; Cytolysis; KW Direct protein sequencing; Hemolysis; Secreted. FT PEPTIDE 1 20 Ponericin-W6. FT /FTId=PRO_0000044199. FT MOD_RES 20 20 Lysine amide. SQ SEQUENCE 20 AA; 2031 MW; 5241E1528A9A98EB CRC64; FIGTALGIAS AIPAIVKLFK //