ID IMPI_GALME STANDARD; PRT; 24 AA. AC P82176; DT 16-OCT-2001 (Rel. 40, Created) DT 16-OCT-2001 (Rel. 40, Last sequence update) DT 16-OCT-2001 (Rel. 40, Last annotation update) DE Metalloproteinase inhibitor (IMPI) (Fragment). OS Galleria mellonella (Wax moth). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Pyraloidea; OC Pyralidae; Galleriinae; Galleria. OX NCBI_TaxID=7137; RN [1] RP SEQUENCE. RC TISSUE=Larval hemolymph; RX MEDLINE=98409271; PubMed=9738891; RA Wedde M., Weise C., Kopacek P., Franke P., Vilcinskas A.; RT "Purification and characterization of an inducible metalloprotease RT inhibitor from the hemolymph of greater wax moth larvae, Galleria RT mellonella."; RL Eur. J. Biochem. 255:535-543(1998). CC -!- FUNCTION: IT INHIBITS THERMOLYSIN AND THE METALLOPROTEASE OF CC B.POLYMYXA. NO ACTIVITY ON TRYPSIN OR CYSTEINPROTEASE PAPAIN. CC -!- INDUCTION: BY LIPOPOLYSACCHARIDE (LPS). CC -!- PTM: FIVE DISULFIDES BONDS ARE PRESENT. CC -!- PTM: THE HEAVY CHAIN MAY BE O-GLYCOSILATED. CC -!- MASS SPECTROMETRY: MW=8360; METHOD=MALDI. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- KW Metalloprotease inhibitor; Glycoprotein. FT NON_TER 1 1 FT NON_TER 24 24 SQ SEQUENCE 24 AA; 2783 MW; 490E278E449F0C25 CRC64; IRCNDKHYCE DGYARDVNGK CIPI //