ID P81914 PRELIMINARY; PRT; 378 AA. AC P81914; DT 01-AUG-1999 (TrEMBLrel. 11, Created) DT 01-AUG-1999 (TrEMBLrel. 11, Last sequence update) DT 01-AUG-1999 (TrEMBLrel. 11, Last annotation update) DE ODORANT RECEPTOR 33B.1 (OR33B.1). GN OR33B.1 OR DOR33B.1 OR DOR73. OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Tracheata; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. RN [1] RP SEQUENCE FROM N.A. RC STRAIN=Y1 CN BW SP; RA CELNIKER S.E., AGHAVANI A., ARCAINA T.T., BAXTER E., DOYLE C.M., RA FARFAN D.E., FLANAGAN J., HOUSTON K.A., HUMMASTI S.R., KARRA K., RA KEARNEY L., KIM S.H., KO C.L., LI M., LOMOTAN M.A., MAZDA P., RA MOK M.S., NIXON K., PACLEB J.M., PARK S., PFEIFFER B., PUNCH D., RA SANTOS R.F., SNIR E., STEVKO V., SUBRAMANIAN S., TOWNE B., WAN K.H., RA WHITELAW K.R., YEE A., ZHANG R., ZIERAN L.L., KIMMEL B.; RL Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION, AND TISSUE SPECIFICITY. RX MEDLINE; 99166868. RA CLYNE P.J., WARR C.G., FREEMAN M.R., LESSING D., KIM J., CARLSON J.R.; RT "A novel family of divergent seven-transmembrane proteins: candidate RT odorant receptors in Drosophila."; RL Neuron 22:327-338(1999). RN [3] RP IDENTIFICATION, AND TISSUE SPECIFICITY. RC STRAIN=OREGON-R; TISSUE=ANTENNA; RX MEDLINE; 99189757. RA VOSSHALL L.B., AMREIN H., MOROZOV P.S., RZHETSKY A., AXEL R.; RT "A spatial map of olfactory receptor expression in the Drosophila RT antenna."; RL Cell 96:725-736(1999). CC -!- FUNCTION: PROBABLE ROLE IN THE ODORANT RESPONSE, BEING AN ODORANT CC RECEPTOR. EXPRESSION DEPENDS ON THE POU-DOMAIN TRANSCRIPTION CC FACTOR ACJ6. CC -!- SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. CC -!- TISSUE SPECIFICITY: EXPRESSED IN THE ANTENNA. CC -!- SIMILARITY: BELONGS TO FAMILY 1 OF G-PROTEIN COUPLED RECEPTORS. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AC006240; -; NOT_ANNOTATED_CDS. DR FLYBASE; FBgn0026392; Or33B.1. DR PROSITE; PS00237; G_PROTEIN_RECEPTOR; FALSE_NEG. KW Hypothetical protein; Transmembrane; G-protein coupled receptor; KW Olfaction; Glycoprotein; Multigene family. FT DOMAIN 1 33 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 34 54 POTENTIAL. FT DOMAIN 55 127 CYTOPLASMIC (POTENTIAL). FT TRANSMEM 128 148 POTENTIAL. FT DOMAIN 149 163 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 164 184 POTENTIAL. FT DOMAIN 185 254 CYTOPLASMIC (POTENTIAL). FT TRANSMEM 255 275 POTENTIAL. FT DOMAIN 276 285 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 286 306 POTENTIAL. FT DOMAIN 307 378 CYTOPLASMIC (POTENTIAL). SQ SEQUENCE 378 AA; 43891 MW; 51E040D6 CRC32; MDSRRKVRSE NLYKTYWLYW RLLGVEGDYP FRRLVDFTIT SFITILFPVH LILGMYKKPQ IQVFRSLHFT SECLFCSYKF FCFRWKLKEI KTIEGLLQDL DSRVESEEER NYFNQNPSRV ARMLSKSYLV AAISAIITAT VAGLFSTGRN LMYLGWFPYD FQATAAIYWI SFSYQAIGSS LLILENLAND SYPPITFCVV SGHVRLLIMR LSRIGHDVKL SSSENTRKLI EGIQDHRKLM KIIRLLRSTL HLSQLGQFLS SGINISITLI NILFFAENNF AMLYYAVFFA AMLIELFPSC YYGILMTMEF DKLPYAIFSS NWLKMDKRYN RSLIILMQLT LVPVNIKAGG IVGIDMSAFF ATVRMAYSFY TLALSFRV //