ID O33A_DROME STANDARD; PRT; 378 AA. AC P81914; DT 16-OCT-2001 (Rel. 40, Created) DT 16-OCT-2001 (Rel. 40, Last sequence update) DT 16-OCT-2001 (Rel. 40, Last annotation update) DE Odorant receptor 33a. GN OR33A OR OR33B.1 OR DOR33B.1 OR DOR73 OR AN3 OR CG16960. OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Tracheata; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7227; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=99389723; PubMed=10458908; RA Gao Q., Chess A.; RT "Identification of candidate Drosophila olfactory receptors from RT genomic DNA sequence."; RL Genomics 60:31-39(1999). RN [2] RP SEQUENCE FROM N.A. RC STRAIN=BERKELEY; RX MEDLINE=20196006; PubMed=10731132; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [3] RP IDENTIFICATION, AND TISSUE SPECIFICITY. RX MEDLINE=99166868; PubMed=10069338; RA Clyne P.J., Warr C.G., Freeman M.R., Lessing D., Kim J., Carlson J.R.; RT "A novel family of divergent seven-transmembrane proteins: candidate RT odorant receptors in Drosophila."; RL Neuron 22:327-338(1999). RN [4] RP IDENTIFICATION, AND TISSUE SPECIFICITY. RC STRAIN=OREGON-R; TISSUE=Antenna; RX MEDLINE=99189757; PubMed=10089887; RA Vosshall L.B., Amrein H., Morozov P.S., Rzhetsky A., Axel R.; RT "A spatial map of olfactory receptor expression in the Drosophila RT antenna."; RL Cell 96:725-736(1999). CC -!- FUNCTION: PROBABLE ROLE IN THE ODORANT RESPONSE, BEING AN ODORANT CC RECEPTOR. CC -!- SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL). CC -!- SIMILARITY: BELONGS TO FAMILY DR-OR OF G-PROTEIN COUPLED CC RECEPTORS. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE003634; AAF53131.1; -. DR FlyBase; FBgn0026392; Or33a. DR InterPro; IPR004117; 7tm_6. DR Pfam; PF02949; 7tm_6; 1. KW Transmembrane; G-protein coupled receptor; Olfaction; Glycoprotein; KW Multigene family. FT DOMAIN 1 33 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 34 54 1 (POTENTIAL). FT DOMAIN 55 62 CYTOPLASMIC (POTENTIAL). FT TRANSMEM 63 83 2 (POTENTIAL). FT DOMAIN 84 127 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 128 148 3 (POTENTIAL). FT DOMAIN 149 163 CYTOPLASMIC (POTENTIAL). FT TRANSMEM 164 184 4 (POTENTIAL). FT DOMAIN 185 254 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 255 275 5 (POTENTIAL). FT DOMAIN 276 285 CYTOPLASMIC (POTENTIAL). FT TRANSMEM 286 306 6 (POTENTIAL). FT DOMAIN 307 355 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 356 376 7 (POTENTIAL). FT DOMAIN 377 378 CYTOPLASMIC (POTENTIAL). FT CARBOHYD 189 189 N-LINKED (GLCNAC...) (POTENTIAL). FT CARBOHYD 330 330 N-LINKED (GLCNAC...) (POTENTIAL). SQ SEQUENCE 378 AA; 43891 MW; D5BE000865EBCA21 CRC64; MDSRRKVRSE NLYKTYWLYW RLLGVEGDYP FRRLVDFTIT SFITILFPVH LILGMYKKPQ IQVFRSLHFT SECLFCSYKF FCFRWKLKEI KTIEGLLQDL DSRVESEEER NYFNQNPSRV ARMLSKSYLV AAISAIITAT VAGLFSTGRN LMYLGWFPYD FQATAAIYWI SFSYQAIGSS LLILENLAND SYPPITFCVV SGHVRLLIMR LSRIGHDVKL SSSENTRKLI EGIQDHRKLM KIIRLLRSTL HLSQLGQFLS SGINISITLI NILFFAENNF AMLYYAVFFA AMLIELFPSC YYGILMTMEF DKLPYAIFSS NWLKMDKRYN RSLIILMQLT LVPVNIKAGG IVGIDMSAFF ATVRMAYSFY TLALSFRV //