ID TEMG_RANTE STANDARD; PRT; 61 AA. AC P79875; DT 01-NOV-1997 (Rel. 35, Created) DT 01-NOV-1997 (Rel. 35, Last sequence update) DT 30-MAY-2000 (Rel. 39, Last annotation update) DE TEMPORIN G PRECURSOR. OS Rana temporaria (European common frog). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana. RN [1] RP SEQUENCE FROM N.A. RC TISSUE=SKIN; RX MEDLINE; 97175050. RA Simmaco M., Mignogna G., Canofeni S., Miele R., Mangoni M.L., RA Barra D.; RT "Temporins, antimicrobial peptides from the European red frog Rana RT temporaria."; RL Eur. J. Biochem. 242:788-792(1996). CC -!- FUNCTION: HAS ANTIBACTERIAL ACTIVITY AGAINST GRAM-NEGATIVE AND CC GRAM-POSITIVE BACTERIA. CC -!- SUBCELLULAR LOCATION: SECRETED. CC -!- SIMILARITY: BELONGS TO THE BREVININ/ESCULENTIN/GAEGURIN/RUGOSIN CC FAMILY. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Y09395; CAA70564.1; -. KW Amphibian skin; Antibiotic; Amidation; Signal; Multigene family. FT SIGNAL 1 22 POTENTIAL. FT PROPEP 23 46 POTENTIAL. FT CHAIN 47 59 TEMPORIN G. FT MOD_RES 59 59 AMIDATION (G-60 PROVIDE AMIDE GROUP). SQ SEQUENCE 61 AA; 7171 MW; EDF5A8BC79DFD9F2 CRC64; MFTLKKSLLL LFFLGTINLS LCEEERDADE ERRDDLEERD VEVEKRFFPV IGRILNGILG K //