ID CD4_MACFU STANDARD; PRT; 458 AA. AC P79184; DT 15-JUL-1998 (REL. 36, CREATED) DT 15-JUL-1998 (REL. 36, LAST SEQUENCE UPDATE) DT 15-JUL-1998 (REL. 36, LAST ANNOTATION UPDATE) DE T-CELL SURFACE GLYCOPROTEIN CD4 PRECURSOR (T-CELL SURFACE ANTIGEN DE T4/LEU-3). GN CD4. OS MACACA FUSCATA FUSCATA (JAPANESE MACAQUE). OC EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; MAMMALIA; EUTHERIA; OC PRIMATES; CATARRHINI; CERCOPITHECIDAE; CERCOPITHECINAE; MACACA. RN [1] RP SEQUENCE FROM N.A. RA HASHIMOTO O., TATSUMI M.; RL SUBMITTED (FEB-1997) TO EMBL/GENBANK/DDBJ DATA BANKS. CC -!- FUNCTION: ACCESSORY PROTEIN FOR MHC CLASS-II ANTIGEN/T-CELL CC RECEPTOR INTERACTION. MAY REGULATE T-CELL ACTIVATION. CC -!- SUBUNIT: ASSOCIATES WITH P56-LCK (BY SIMILARITY). CC -!- SUBCELLULAR LOCATION: TYPE I MEMBRANE PROTEIN. CC -!- SIMILARITY: BELONGS TO THE IMMUNOGLOBULIN SUPERFAMILY. CONTAINS CC ONE V-LIKE AND 3 C2-LIKE DOMAINS. CC -------------------------------------------------------------------------- CC This SWISS-PROT entry is copyright. It is produced through a collaboration CC between the Swiss Institute of Bioinformatics and the EMBL outstation - CC the European Bioinformatics Institute. There are no restrictions on its CC use by non-profit institutions as long as its content is in no way CC modified and this statement is not removed. Usage by and for commercial CC entities requires a license agreement (See http://www.isb-sib.ch/announce/ CC or send an email to license@isb-sib.ch). CC -------------------------------------------------------------------------- CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; D63348; G1834299; -. DR PFAM; PF00047; ig; 1. DR HSSP; P01730; 1WBR. KW IMMUNOGLOBULIN FOLD; TRANSMEMBRANE; GLYCOPROTEIN; T-CELL; MHC; SIGNAL; KW LIPOPROTEIN. FT SIGNAL 1 25 BY SIMILARITY. FT CHAIN 26 458 T-CELL SURFACE GLYCOPROTEIN CD4. FT DOMAIN 26 396 EXTRACELLULAR (POTENTIAL). FT TRANSMEM 397 418 POTENTIAL. FT DOMAIN 419 458 CYTOPLASMIC (POTENTIAL). FT DOMAIN 26 125 IG-LIKE V-TYPE DOMAIN. FT DOMAIN 126 203 IG-LIKE C2-TYPE DOMAIN. FT DOMAIN 204 317 IG-LIKE C2-TYPE DOMAIN. FT DOMAIN 318 374 IG-LIKE C2-TYPE DOMAIN. FT CARBOHYD 42 42 POTENTIAL. FT CARBOHYD 296 296 BY SIMILARITY. FT CARBOHYD 325 325 BY SIMILARITY. FT DISULFID 41 109 BY SIMILARITY. FT DISULFID 155 184 BY SIMILARITY. FT DISULFID 328 370 BY SIMILARITY. FT LIPID 419 419 PALMITATE (BY SIMILARITY). FT LIPID 422 422 PALMITATE (BY SIMILARITY). SQ SEQUENCE 458 AA; 50828 MW; 8D4CD298 CRC32; MNRGIPFRHL LLVLQLALLP AVTQGKKVVL GKKGDTVELT CNASQKKNTQ FHWKNSNQIK ILGIQGSFLT KGPSKLSDRA DSRKSLWDQG CFSMIIKNLK IEDSDTYICE VENKKEEVEL LVFGLTANSD THLLEGQSLT LTLESPPGSS PSVKCRSPGG KNIQGGRTIS VPQLERQDSG TWTCTVSQDQ KTVEFKIDIV VLAFQKASST VYKKEGEQVE FSFPLAFTLE KLTGSGELWW QAERASSSKS WITFDLKNKE VSVKRVTQDP KLQMGKKLPL HLTLPQALPQ YAGSGNLTLA LEAKTGKLHQ EVNLVVMRAA QFQENLTCEV WGPTSPKLTL SLKLENKGAT VSKQAKAVWV LNPEAGMWQC LLSDSGQVLL ESNIKVVPTW PTPVQPMALI VLGGVAGLLL FTGLGIFFCV RCRHRRRQAE RMSQIKRLLS EKKTCQCPHR FQKTCSPI //