ID GPO_SYNY3 Reviewed; 169 AA. AC P74250; DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot. DT 01-FEB-1997, sequence version 1. DT 01-SEP-2009, entry version 49. DE RecName: Full=Putative glutathione peroxidase; DE EC=1.11.1.9; GN OrderedLocusNames=slr1171; OS Synechocystis sp. (strain PCC 6803). OC Bacteria; Cyanobacteria; Chroococcales; Synechocystis. OX NCBI_TaxID=1148; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX MEDLINE=97061201; PubMed=8905231; DOI=10.1093/dnares/3.3.109; RA Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., RA Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., RA Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., RA Shimpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., RA Tabata S.; RT "Sequence analysis of the genome of the unicellular cyanobacterium RT Synechocystis sp. strain PCC6803. II. Sequence determination of the RT entire genome and assignment of potential protein-coding regions."; RL DNA Res. 3:109-136(1996). CC -!- CATALYTIC ACTIVITY: 2 glutathione + H(2)O(2) = glutathione CC disulfide + 2 H(2)O. CC -!- SIMILARITY: Belongs to the glutathione peroxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BA000022; BAA18344.1; -; Genomic_DNA. DR PIR; S75885; S75885. DR RefSeq; NP_441664.1; -. DR HSSP; P00435; 1GP1. DR STRING; P74250; -. DR PeroxiBase; 3755; SYspGPx01. DR GeneID; 954977; -. DR GenomeReviews; BA000022_GR; slr1171. DR KEGG; syn:slr1171; -. DR NMPDR; fig|1148.1.peg.1765; -. DR HOGENOM; P74250; -. DR OMA; P74250; SFCELNF. DR BioCyc; SSP1148:SLR1171-MON; -. DR GO; GO:0004602; F:glutathione peroxidase activity; IEA:EC. DR GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW. DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro. DR InterPro; IPR000889; Glutathione_peroxidase. DR InterPro; IPR012335; Thioredoxin_fold. DR Gene3D; G3DSA:3.40.30.10; Thioredoxin_fold; 1. DR PANTHER; PTHR11592; Glut_peroxidase; 1. DR Pfam; PF00255; GSHPx; 1. DR PIRSF; PIRSF000303; Glutathion_perox; 1. DR PRINTS; PR01011; GLUTPROXDASE. DR PROSITE; PS00460; GLUTATHIONE_PEROXID_1; 1. DR PROSITE; PS00763; GLUTATHIONE_PEROXID_2; 1. DR PROSITE; PS51355; GLUTATHIONE_PEROXID_3; 1. PE 3: Inferred from homology; KW Complete proteome; Oxidoreductase; Peroxidase. FT CHAIN 1 169 Putative glutathione peroxidase. FT /FTId=PRO_0000066663. FT ACT_SITE 41 41 By similarity. SQ SEQUENCE 169 AA; 18452 MW; 0DC382089FCE39E2 CRC64; MTAQANNTIY GFSANALDGS PVALRDFEGK VLLIVNTASQ CGFTPQYQGL QALYNRFGDR GFTVLGFPCN QFGQQEPGGS GEIKNFCETR YGVTFPLFEK VEVNGPNAHP LFKFLTAASP GMAIPFLGGA EDIKWNFTKF LVDRQGKVVK RYGSIAKPDE IAADIEKLL //